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Klrb1a recombinant protein
Klrb1a Protein, Mouse, Recombinant (His Tag)
Gene Names
Klrb1a; Ly55a; NKRP12; Nkrp1a; ly-55A; NKR-P1A; Nkrp1-a; NKR-P1.7
Purity
>95% as determined by SDS-PAGE
Synonyms
Klrb1a; Klrb1a Protein; Mouse; Recombinant (His Tag); Mouse NKR-P1A/Klrb1a Protein (His Tag); ly-55A Protein; Ly55a Protein; NKR-P1.7 Protein; NKR-P1A Protein; Nkrp1-a Protein; NKRP12 Protein; Nkrp1a Protein; killer cell lectin-like receptor subfamily B member 1A; Klrb1a recombinant protein
Host
HEK293 Cells
Purity/Purification
>95% as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Sequence
Gln67-His227
Species
Mouse
Endotoxin
<1.0EU per ug of the protein as determined by the LAL method
Predicted N Terminal
His
Tag
N-His
Protein Construction
A DNA sequence encoding the secreted form of mouse Klrb1a (P27811)(Gln 67-His 227) was fused with a polyhistidine tag at the N-terminus.
Reconstitution
A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.
They are shipped out with blue ice.
SDS-Page
SDS-Page
References
Plougastel B, et al. (2001) Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f. Immunogenetics 53: 592-598.Kogelberg H, et al. (2000) Expression in Escherichia coli, folding in vitro, and characterization of the carbohydrate recognition domain of the natural killer cell receptor NKR-P1A. Protein Expr Purif. 20(1): 10-20.Grazia Cifone M, et al. (1997) NKR-P1A stimulation of arachidonate-generating enzymes in rat NK cells is associated with granule release and cytotoxic activity. J Immunol. 159(1): 309-17.Josien R, et al. (1997) Rat spleen dendritic cells express natural killer cell receptor protein 1 (NKR-P1) and have cytotoxic activity to select targets via a Ca2+-dependent mechanism. J Exp Med. 186: 467-472.Ryan JC, et al. (1995) NKR-P1A is a target-specific receptor that activates natural killer cell cytotoxicity. J Exp Med. 181(5): 1911-5.Lanier L L, et al. (1994) Human NKR-P1A: a disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol. 153: 2417-2428.Chambers W, et al. (1989) Monoclonal antibody to a triggering structure expressed on rat natural killer cells and adherent lymphokine-activated killer cells. J Exp Med. 169: 1373-1389.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
25,782 Da
NCBI Official Full Name
killer cell lectin-like receptor subfamily B member 1A isoform 2
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily B member 1A
NCBI Official Symbol
Klrb1a
NCBI Official Synonym Symbols
Ly55a; NKRP12; Nkrp1a; ly-55A; NKR-P1A; Nkrp1-a; NKR-P1.7
NCBI Protein Information
killer cell lectin-like receptor subfamily B member 1A; NKR-P1 2; lymphocyte antigen 55A; natural killer cell receptor-P1; CD161 antigen-like family member A; lymphocyte antigen 55 complex, locus A; natural killer cell surface protein P1-2; natural killer
UniProt Protein Name
Killer cell lectin-like receptor subfamily B member 1A
Protein Family
UniProt Gene Name
Klrb1a
UniProt Synonym Gene Names
Ly55; Ly55a; Nkrp1a; NKR-P1A; Ly-55A; NKR-P1 2
UniProt Entry Name
KLRBA_MOUSE
Uniprot Description
Function: Plays a stimulatory role on natural killer (NK) cell cytotoxicity. Ref.6
Subunit structure: Homodimer; disulfide-linked. Interacts with tyrosine kinase LCK
By similarity. Ref.8
Subcellular location: Membrane; Single-pass type II membrane protein.
Tissue specificity: Expressed in natural killer cells.
Sequence similarities: Contains 1 C-type lectin domain.
Research Articles on Klrb1a
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Product Notes
The Klrb1a klrb1a (Catalog #AAA8122992) is a Recombinant Protein produced from HEK293 Cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Gln67-His2 27. It is sometimes possible for the material contained within the vial of "Klrb1a, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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