NK1.1/KLRB1F Recombinant Protein | KLRB1F recombinant protein

NK1.1/KLRB1F Protein, Mouse, Recombinant (hFc Tag)

Cat. Num. AAA8123000

• Gene Names: Klrb1f; Nkrp1f; Nkr-p1f; Nkrp1-f; A630024B12Rik
• Purity: >88% as determined by SDS-PAGE
• Synonyms: NK1.1/KLRB1F; NK1.1/KLRB1F Protein; Mouse; Recombinant (hFc Tag); Mouse KLRB1F/NKR-P1F Protein (Fc Tag); A630024B12Rik Protein; MGC130065 Protein; MGC130066 Protein; Nkr-p1f Protein; Nkrp1-f Protein; Nkrp1f Protein; killer cell lectin-like receptor subfamily B member 1F; KLRB1F recombinant protein

• Host: HEK293 Cells
• Purity/Purification: >88% as determined by SDS-PAGE
• Form/Format: Lyophilized from sterile PBS, pH7.4. Normally 5%-8% trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Sequence: Gln67-Val217

• Species: Mouse
• Endotoxin: <1.0EU per ug of the protein as determined by the LAL method
• Predicted N Terminal: Glu
• Tag: N-human IgG1-Fc
• Protein Construction: A DNA sequence encoding the extracellular domain of mouse KLRB1F (Q8VD98)(Gln 67-Val 217) was fused with the Fc region of human IgG1 at the N-terminus.
• Reconstitution: A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information.
• Preparation and Storage: Samples are stable for up to twelve months from date of receipt at -20 degree C to -80 degree C. Store it under sterile conditions at -20 degree C to -80 degree C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.; In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid.; They are shipped out with blue ice.

SDS-Page

References

Kveberg L, et al. (2011) Phylogenetic and functional conservation of the NKR-P1F and NKR-P1G receptors in rat and mouse. Immunogenetics. 63(7): 429-36.Aust JG, et al. (2009) The expression and function of the NKRP1 receptor family in C57BL/6 mice. J Immunol. 183(1): 106-16.Tian W, et al. (2005) C-type lectin OCILRP2/Clr-g and its ligand NKRP1f costimulate T cell proliferation and IL-2 production. Cell Immunol. 234(1): 39-53.Plougastel B, et al. (2001) Analysis of a 1-Mb BAC contig overlapping the mouse Nkrp1 cluster of genes: cloning of three new Nkrp1 members, Nkrp1d, Nkrp1e, and Nkrp1f. Immunogenetics. 53(7): 592-8.

NCBI and Uniprot Product Information

• NCBI GI #: 25092655
• NCBI GeneID: 232408
• NCBI Accession #: NP_694734.1
• NCBI GenBank Nucleotide #: NM_153094.2
• UniProt Accession #: Q8VD98; Q1AFZ8; Q3TDT3; Q8C9Q1
• Molecular Weight: 24,681 Da
• NCBI Official Full Name: killer cell lectin-like receptor subfamily B member 1F
• NCBI Official Synonym Full Names: killer cell lectin-like receptor subfamily B member 1F
• NCBI Official Symbol: Klrb1f
• NCBI Official Synonym Symbols: Nkrp1f; Nkr-p1f; Nkrp1-f; A630024B12Rik
• NCBI Protein Information: killer cell lectin-like receptor subfamily B member 1F
• UniProt Protein Name: Killer cell lectin-like receptor subfamily B member 1F
• Protein Family: Killer cell lectin-like receptor subfamily
• UniProt Gene Name: Klrb1f
• UniProt Synonym Gene Names: Nkrp1f

Uniprot Description

Binds CLEC2I/Clr-g leading to activation of natural killer cells or costimulation of IL-2 production and proliferation of T-cells in response to antigen stimulation. May contribute to the formation of the immunological synapse between T-cells and antigen-presenting dendritic cells.