Inosine triphosphate pyrophosphatase (ITPA) Recombinant Protein | ITPA recombinant protein
Recombinant Bovine Inosine triphosphate pyrophosphatase (ITPA)
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Inosine triphosphate pyrophosphatase (ITPA); Recombinant Bovine Inosine triphosphate pyrophosphatase (ITPA); ITPA recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
2-208, full length protein
Sequence
AASLAGKKIVFVTGNAKKLEEVIQILGDKFPCTLVAQKIDLPEYQGEPDEISIRKCQEAARQVQGPVLVEDTCLCFNALGGLPGPYIKWFLEKLKPEGLHQLLEGFQDKSAYALCTFAFSTGDPNEPVRLFRGRTMGRIVVPRGCRDFGWDPCFQPDGYEQTYAEMPKAEKNTISHRFRALLALQEYFSSLTPGVGDDHPSWGSGEG
Sequence Length
207
Species
Bovine
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
Related Product Information for ITPA recombinant protein
This protein hydrolyzes inosine triphosphate and deoxyinosine triphosphate to the monophosphate nucleotide and diphosphate. The encoded protein, which is a member of the HAM1 NTPase protein family, is found in the cytoplasm and acts as a homodimer. Defects in the encoded protein can result in inosine triphosphate pyrophosphorylase deficiency. Two transcript variants encoding two different isoforms have been found for this gene. Also, at least two other transcript variants have been identified which are probably regulatory rather than protein-coding.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
23,061 Da
NCBI Official Full Name
inosine triphosphate pyrophosphatase
NCBI Official Synonym Full Names
inosine triphosphatase
NCBI Official Symbol
ITPA
NCBI Protein Information
inosine triphosphate pyrophosphatase
UniProt Protein Name
Inosine triphosphate pyrophosphatase
UniProt Gene Name
ITPA
UniProt Synonym Gene Names
ITPase; Inosine triphosphatase; NTPase
Uniprot Description
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
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Product Notes
The ITPA itpa (Catalog #AAA1446659) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 2-208, full length protein. The amino acid sequence is listed below: AASLAGKKIV FVTGNAKKLE EVIQILGDKF PCTLVAQKID LPEYQGEPDE ISIRKCQEAA RQVQGPVLVE DTCLCFNALG GLPGPYIKWF LEKLKPEGLH QLLEGFQDKS AYALCTFAFS TGDPNEPVRL FRGRTMGRIV VPRGCRDFGW DPCFQPDGYE QTYAEMPKAE KNTISHRFRA LLALQEYFSS LTPGVGDDHP SWGSGEG. It is sometimes possible for the material contained within the vial of "Inosine triphosphate pyrophosphatase (ITPA), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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