ITLN1 recombinant protein

Recombinant Human ITLN1 Protein

Cat. Num. AAA8249325

• Gene Names: ITLN1; HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
• Reactivity: Human
• Applications: ELISA, Western Blot, SDS-Page
• Purity: Greater than 95% as determined by reducing SDS-PAGE.
• Synonyms: ITLN1; Recombinant Human ITLN1 Protein; INTL; ITLN; LFR; Intelectin-1; ITLN-1; Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin; ITLN1 recombinant protein

• Host: E Coli
• Reactivity: Human
• Purity/Purification: Greater than 95% as determined by reducing SDS-PAGE.
• Form/Format: Lyophilized from a 0.2 muM filtered solution of 50mM Tris, 100mM NaCl, 5mM GSH, 0.5mM GSSG, pH 8.0.
• Sequence: MNHKVHHHHH HMTDEANTYF KEWTCSSSPS LPRSCKEIKD ECPSAFDGLY FLRTENGVIY QTFCDMTSGG GGWTLVASVH ENDMRGKCTV GDRWSSQQGS KAVYPEGDGN WANYNTFGSA EAATSDDYKN PGYYDIQAKD LGIWHVPNKS PMQHWRNSSL LRYRTDTGFL QTLGHNLFGI YQKYPVKYGE GKCWTDNGPV IPVVYDFGDA QKTASYYSPY GQREFTAGFV QFRVFNNERA ANALCAGMRV TGCNTEHHCI GGGGYFPEAS PQQCGDFSGF DWSGYGTHVG YS
• Sequence Length: 313

• Applicable Applications for ITLN1 recombinant protein: ELISA (EIA),Western Blot (WB), SDS-PAGE, Mass Spectrometry (MS)
• Endotoxin: Less than 0.1 ng/mug (1 IEU/mug) as determined by LAL test.
• Directions for Use: Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 mug/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Preparation and Storage: Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks. Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.

Related Product Information for ITLN1 recombinant protein

Recombinant Human ITLN1 Protein is produced by our E Coli expression system and the target gene encoding Thr19-Ser298 is expressed with a 6His tag at the N-terminus.

NCBI and Uniprot Product Information

• NCBI GI #: 31542986
• NCBI GeneID: 55600
• NCBI Accession #: NP_060095.2
• NCBI GenBank Nucleotide #: NM_017625.2
• UniProt Accession #: Q8WWA0; Q5IWS4; Q5VYI4; Q6YDJ3; Q9NP67
• Molecular Weight: 34,962 Da
• NCBI Official Full Name: intelectin-1
• NCBI Official Synonym Full Names: intelectin 1
• NCBI Official Symbol: ITLN1
• NCBI Official Synonym Symbols: HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin
• NCBI Protein Information: intelectin-1
• UniProt Protein Name: Intelectin-1
• Protein Family: Intelectin
• UniProt Gene Name: ITLN1
• UniProt Synonym Gene Names: INTL; ITLN; LFR; ITLN-1
• UniProt Entry Name: ITLN1_HUMAN

Uniprot Description

ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism.

Protein type: Membrane protein, GPI anchor

Chromosomal Location of Human Ortholog: 1q21.3

Cellular Component: brush border membrane; lipid raft; receptor complex

Molecular Function: calcium ion binding

Biological Process: positive regulation of glucose import; positive regulation of protein amino acid phosphorylation; response to nematode