Typical Testing Data/Standard Curve (for reference only)
Rat Insulin-like 3 ELISA Kit | Insl3 elisa kit
Rat Insulin-like 3 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
ligand for LGR8; functions in testis descent [RGD, Feb 2006]
Uniprot Description
INSL3: Seems to play a role in testicular function. May be a trophic hormone with a role in testicular descent in fetal life. Is a ligand for LGR8 receptor. Defects in INSL3 seems to be a cause of cryptorchidism (CRYPTO); also known as impaired testicular descent. It is one of the most frequent congenital abnormalities in humans, involving 2-5% of male births. Cryptorchidism is associated with increased risk of infertility and testicular cancer. The frequency of INSL3 gene mutations as a cause of cryptorchidism is low. Belongs to the insulin family.
Protein type: Secreted, signal peptide; Secreted
Cellular Component: extracellular space; perinuclear region of cytoplasm
Molecular Function: G-protein-coupled receptor binding; hormone activity; protease binding
Biological Process: G-protein signaling, adenylate cyclase inhibiting pathway; gonad development; in utero embryonic development; male gonad development; negative regulation of apoptosis; negative regulation of cell proliferation; oocyte maturation; positive regulation of cAMP biosynthetic process; positive regulation of cell proliferation
Research Articles on Insl3
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Product Notes
The Rat Insl3 insl3 (Catalog #AAA2886543) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2886543 ELISA Kit recognizes Rat Insl3. It is sometimes possible for the material contained within the vial of "Insulin-like 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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