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CAMK2 beta Active Protein | CAMK2beta active protein

Recombinant Human CAMK2 beta (N-His tag)

Gene Names
CAMK2B; CAM2; CAMK2; CAMKB; MRD54
Purity
70%-90%
Synonyms
CAMK2 beta; Recombinant Human CAMK2 beta (N-His tag); CAMKB; CAM2; CAMK2; MGC29528; CAMK2beta active protein
Ordering
For Research Use Only!
Host
Insect Cells
Purity/Purification
70%-90%
Form/Format
Liquid; 50mM NaPhosphate, pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol.
Sequence Length
4056
Bioactivity
The specific activity of CAMK2beta was determined to be 5670 nmol/min/mg as per activity assay protocol.
Preparation and Storage
Store product at-70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Related Product Information for CAMK2beta active protein
CAMK2beta belongs to the serine/threonine protein kinase family and to the type II multifunctional Ca(2+)/calmodulin-dependent protein kinase subfamily. CAMK2beta showed wide tissue and cell distribution, and one of CAMK2beta variant predominated in adult brain. The ratio of CAMK2a and CAMK2beta protein levels were inversely related during activity in hippocampal neurons. CAMK2beta is a prominent kinase in the central nervous system and may function in long-term potentiation and neurotransmitter release.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
816
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
58.0 kDa
NCBI Official Full Name
Homo sapiens calcium/calmodulin dependent protein kinase II beta (CAMK2B), transcript variant 5, mRNA
NCBI Official Synonym Full Names
calcium/calmodulin dependent protein kinase II beta
NCBI Official Symbol
CAMK2B
NCBI Official Synonym Symbols
CAM2; CAMK2; CAMKB; MRD54
NCBI Protein Information
calcium/calmodulin-dependent protein kinase type II subunit beta

NCBI Description

The product of this gene belongs to the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. In mammalian cells, the enzyme is composed of four different chains: alpha, beta, gamma, and delta. The product of this gene is a beta chain. It is possible that distinct isoforms of this chain have different cellular localizations and interact differently with calmodulin. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2014]

Research Articles on CAMK2beta

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Product Notes

The CAMK2beta (Catalog #AAA4160051) is an Active Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CAMK2 beta, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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