Human Cysteine-rich protein 1 ELISA Kit | CRIP1 elisa kit

Human Cysteine-rich protein 1 ELISA Kit

Cat. Num. AAA2888127

• Gene Names: CRIP1; CRHP; CRIP; CRP1; CRP-1
• Reactivity: Human
• Synonyms: Cysteine-rich protein 1; Human Cysteine-rich protein 1 ELISA Kit; CRP-1; Cysteine-rich heart protein; CRHP; hCRHP; Cysteine-rich intestinal protein; CRIP; CRIP1; CRP1; CRIP1 elisa kit

• Reactivity: Human
• Specificity: Recombinant and natural Human Cysteine-rich protein 1,CRP-1
• Sequence Length: 77

• Samples: Serum, plasma, tissue homogenates, cell culture supernates or other biological fluids
• Detection Range: 0.156-10 ng/mL
• Sensitivity: < 0.078 ng/mL
• Intra-assay Precision: <=7.9%
• Inter-assay Precision: <=9.2%
• Preparation and Storage: For long term storage, please store the entire kit at -20 degree C.

Typical Testing Data/Standard Curve (for reference only)

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Related Product Information for CRIP1 elisa kit

Intended Uses: This immunoassay kit allows for the in vitro quantitative determination of target antigen concentrations in serum, plasma, tissue homogenates, cell culture supernates or other biological fluids.

Principle of the Assay: The microtiter plate provided in this kit has been pre-coated with an antibody specific to target antigen. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific for target antigen and then avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. Then a TMB substrate solution is added to each well. Only those wells that contain target antigen, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The concentration of target antigen in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 4503047
• NCBI GeneID: 1396
• NCBI Accession #: NP_001302.1
• NCBI GenBank Nucleotide #: NM_001311.4
• Molecular Weight: 8,533 Da
• NCBI Official Full Name: cysteine-rich protein 1
• NCBI Official Synonym Full Names: cysteine rich protein 1
• NCBI Official Symbol: CRIP1
• NCBI Official Synonym Symbols: CRHP; CRIP; CRP1; CRP-1
• NCBI Protein Information: cysteine-rich protein 1
• UniProt Protein Name: Cysteine-rich protein 1
• Protein Family: Cysteine-rich protein
• UniProt Gene Name: CRIP1
• UniProt Synonym Gene Names: CRIP; CRP1; CRP-1; CRHP; hCRHP; CRIP
• UniProt Entry Name: CRIP1_HUMAN

NCBI Description

Cysteine-rich intestinal protein (CRIP) belongs to the LIM/double zinc finger protein family, members of which include cysteine- and glycine-rich protein-1 (CSRP1; MIM 123876), rhombotin-1 (RBTN1; MIM 186921), rhombotin-2 (RBTN2; MIM 180385), and rhombotin-3 (RBTN3; MIM 180386). CRIP may be involved in intestinal zinc transport (Hempe and Cousins, 1991 [PubMed 1946385]).[supplied by OMIM, Mar 2008]

Uniprot Description

CRIP1: a LIM protein which is developmentally regulated in heart. May have a role in zinc absorption and may function as an intracellular zinc transport protein. The CRIP1 gene is hypomethylated in prostate cancer.

Protein type: DNA-binding

Chromosomal Location of Human Ortholog: 14q32.33

Cellular Component: cytoplasm

Molecular Function: AT DNA binding; DNA bending activity; peptide binding; zinc ion binding

Biological Process: cell proliferation; DNA damage response, signal transduction resulting in induction of apoptosis; heart development; immune response; regulation of gene expression; response to organic substance; response to zinc ion