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ANKK1 active protein

Recombinant Human ANKK1 (SGK288) (N-GST tag)

Gene Names
ANKK1; PKK2; sgK288
Purity
70%-90%
Synonyms
ANKK1; Recombinant Human ANKK1 (SGK288) (N-GST tag); X-kinase; PKK2; SGK288; ANKK1 active protein
Ordering
For Research Use Only!
Host
Insect Cells
Purity/Purification
70%-90%
Form/Format
Liquid; 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Sequence Length
2553
Bioactivity
The specific activity of ANKK1 (SGK288) was determined to be 80 nmol/min/mg as per activity assay protocol
Preparation and Storage
Store product at-70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature.
For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Related Product Information for ANKK1 active protein
ANKK1 or ankyrin repeat and kinase domain containing 1 is belongs to the Ser/Thr protein kinase family, and protein kinase superfamily that involved in signal transduction pathways. ANKK1 is closely linked to DRD2 gene on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene and it was determined to be located in exon 8 of ANKK1 gene where it causes a nonconservative amino acid substitution.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
115.0 kDa
NCBI Official Full Name
Homo sapiens ankyrin repeat and kinase domain containing 1 (ANKK1), mRNA
NCBI Official Synonym Full Names
ankyrin repeat and kinase domain containing 1
NCBI Official Symbol
ANKK1
NCBI Official Synonym Symbols
PKK2; sgK288
NCBI Protein Information
ankyrin repeat and protein kinase domain-containing protein 1
UniProt Protein Name
Ankyrin repeat and protein kinase domain-containing protein 1
UniProt Gene Name
ANKK1
UniProt Synonym Gene Names
PKK2; SGK288; SgK288
UniProt Entry Name
ANKK1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]

Uniprot Description

ANKK1: belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]

Protein type: Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; TKL group; RIPK family

Chromosomal Location of Human Ortholog: 11q23.2

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: protein amino acid phosphorylation

Research Articles on ANKK1

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Product Notes

The ANKK1 ankk1 (Catalog #AAA4160030) is an Active Protein produced from Insect Cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ANKK1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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