Rabbit anti-Mouse KIF5C Polyclonal Antibody | anti-KIF5C antibody
KIF5C Antibody (C-term)
Wang, X., et al. Cell 136(1):163-174(2009)
Schafer, B., et al. Cell. Mol. Life Sci. 66(2):339-349(2009)
Schafer, B., et al. Biochem. Biophys. Res. Commun. 375(2):179-183(2008)
Cho, K.I., et al. Traffic 8(12):1722-1735(2007)
NCBI and Uniprot Product Information
NCBI Description
The protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein, which acts as a tetramer by associating with another heavy chain and two light chains, interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations-2. Two transcript variants, one protein-coding and the other non-protein coding, have been found for this gene. [provided by RefSeq, Jul 2015]
Uniprot Description
KIF5C: Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. Belongs to the kinesin-like protein family. Kinesin subfamily. 2 isoforms of the human protein are produced by alternative splicing.
Chromosomal Location of Human Ortholog: 2q23.1
Cellular Component: kinesin complex; microtubule; cytoplasm
Molecular Function: protein binding; plus-end-directed microtubule motor activity; microtubule binding; ATPase activity; microtubule motor activity; ATP binding
Biological Process: axon guidance; protein localization; mRNA transport; metabolic process; organelle organization and biogenesis; cytoskeleton-dependent intracellular transport; microtubule-based movement
Disease: Cortical Dysplasia, Complex, With Other Brain Malformations 2
Research Articles on KIF5C
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Product Notes
The KIF5C kif5c (Catalog #AAA9209534) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 758-786. The KIF5C Antibody (C-term) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's KIF5C can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the KIF5C kif5c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "KIF5C, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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