Rabbit anti-Human ANKK1 Polyclonal Antibody | anti-ANKK1 antibody

ANKK1 Polyclonal Antibody

Cat. Num. AAA9140772

• Gene Names: ANKK1; PKK2; sgK288
• Reactivity: Human
• Applications: Western Blot
• Purity: Affinity Purification
• Synonyms: ANKK1; Polyclonal Antibody; ANKK1 Polyclonal Antibody; PKK2; ankyrin repeat and kinase domain containing 1; anti-ANKK1 antibody

• Host: Rabbit
• Reactivity: Human
• Clonality: Polyclonal
• Isotype: IgG
• Purity/Purification: Affinity Purification
• Form/Format: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
• Concentration: 2.06 mg/ml (varies by lot)
• Sequence Length: 765

• Applicable Applications for anti-ANKK1 antibody: Western Blot (WB)
• Application Notes: WB: 1:500-1:2000
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human ANKK1 (NP_848605.1).
• Immunogen Sequence: MAADPTELRLGSLPVFTRDDFEGDWRLVASGGFSQVFQARHRRWRTEYAIKCAPCLPPDAASSDVNYLIEEAAKMKKIKFQHIVSIYGVCKQPLGIVMEFMANGSLEKVLSTHSLCWKLRFRIIHETSLAMNFLHSIKPPLLHLDLKPGNILLDSNMHVKISDFGLSKWMEQSTRMQYIERSALRGMLSYIPPEMFLESNKAPGPKYDVYSFAIVIWELLTQKKPYSGFNMMMIIIRVAAGMRPSLQPVSDQWPSEAQQMVDLMKRCWDQDPKKRPCFLDITIETDILLSLLQSRVAVPE
• Positive Samples: U-87MG
• Preparation and Storage: Store at -20 degree C. Avoid freeze/thaw cycles.

Western Blot (WB)

(Western blot-ANKK1 Polyclonal Antibody)

Related Product Information for anti-ANKK1 antibody

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP.

NCBI and Uniprot Product Information

• NCBI GI #: 30425444
• NCBI GeneID: 255239
• NCBI Accession #: NP_848605.1
• NCBI GenBank Nucleotide #: NP_848605.1
• UniProt Accession #: Q8NFD2
• Molecular Weight: Calculated: 84kDa; Observed: 85kDa
• NCBI Official Full Name: ankyrin repeat and protein kinase domain-containing protein 1
• NCBI Official Synonym Full Names: ankyrin repeat and kinase domain containing 1
• NCBI Official Symbol: ANKK1
• NCBI Official Synonym Symbols: PKK2; sgK288
• NCBI Protein Information: ankyrin repeat and protein kinase domain-containing protein 1
• UniProt Protein Name: Ankyrin repeat and protein kinase domain-containing protein 1
• Protein Family: Ankyrin repeat and protein kinase domain-containing protein
• UniProt Gene Name: ANKK1
• UniProt Synonym Gene Names: PKK2; SGK288; SgK288
• UniProt Entry Name: ANKK1_HUMAN

NCBI Description

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]

Uniprot Description

ANKK1: belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]

Protein type: Protein kinase, TKL; Kinase, protein; Protein kinase, Ser/Thr (non-receptor); EC 2.7.11.1; TKL group; RIPK family

Chromosomal Location of Human Ortholog: 11q23.2

Molecular Function: protein serine/threonine kinase activity; ATP binding

Biological Process: protein amino acid phosphorylation