Structure
Selurampanel, Inhibitor
Selurampanel
Purity
>98% (HPLC)
Synonyms
Selurampanel; BGG 492; inhibitor
Purity/Purification
>98% (HPLC)
Target
iGluR
Receptor
iGluR
Chemical Name
N-(7-isopropyl-6-(1-methyl-1H-pyrazol-5-yl)-2, 4-dioxo-1, 4-dihydroquinazolin-3(2H)-yl)methanesulfonamide
SMILES
CS(=O)(NN1C(NC2=C(C=C(C3=CC=NN3C)C(C(C)C)=C2)C1=O)=O)=O
Molecular Formula
C16H19N5O4S
CAS Number
912574-69-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Selurampanel, inhibitor
Selurampanel (BGG 492) is a selective, orally active and competitive AMPA receptor (AMPAR) antagonist with IC50 of 0.19uM; displays >100-fold selectivity overnMDA and kainate receptors; demonstrates excellent oral potency against MES-induced generalized tonic-clonic seizures in rodents as well as significant activity in patients suffering from various forms of epilepsy.Epilepsy Discontinued
Product Categories/Family for Selurampanel, inhibitor
References
1. Orain D, et al. ChemMedChem. 2017 Feb 3; 12 (3):197-201.
2. Kasteleijn-Nolst Trenitie D, et al. Epilepsia. 2015 Jun; 56 (6):924-32.
3. Faught E. Expert Opin Investig Drugs. 2014 Jan; 23 (1):107-13.
2. Kasteleijn-Nolst Trenitie D, et al. Epilepsia. 2015 Jun; 56 (6):924-32.
3. Faught E. Expert Opin Investig Drugs. 2014 Jan; 23 (1):107-13.
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Product Notes
The Selurampanel (Catalog #AAA3606545) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Selurampanel, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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