Structure
NS-1209 Biochemical
NS-1209
Purity
>98% (HPLC)
Synonyms
NS-1209; NS1209; SPD502; NS-1209 biochemical
Purity/Purification
>98% (HPLC)
Target
iGluR
Receptor
iGluR
Chemical Name
(R, Z)-2-(((5-(4-(N, N-dimethylsulfamoyl)phenyl)-8-methyl-2-oxo-1, 2, 6, 7, 8, 9-hexahydro-3H-pyrrolo[3, 2-h]isoquinolin-3-ylidene)amino)oxy)-4-hydroxybutanoic acid
SMILES
O=C(O)[C@H](O/N=C1C2=C(C(C3)=C(CCN3C)C(C4=CC=C(C=C4)S(N(C)C)(=O)=O)=C2)NC/1=O)CCO
Molecular Formula
C24H28N4O7S
CAS Number
245063-59-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for NS-1209 biochemical
A selective, water-soluble, in vivo long-lasting AMPA antagonist with Ki of 43nM; display selectivity for the [3H] AMPA over the [3H]kainate-(IC50=81uM), [3H]CGS19755, and [3H]glycine-binding sites (IC50 >30uM) in rat cortical membranes; inhibits AMPA-induced currents in cortical neurons with IC50 of 0.15uM; blocks AMPA-evoked spike activity in rat hippocampus (ED50=6.1mg/kg). Stroke Phase 2 Discontinued
Product Categories/Family for NS-1209 biochemical
References
1. Nielsen EO, et al. J Pharmacol Exp Ther. 1999 Jun; 289 (3):1492-501.
2. Erichsen HK, et al. Pain. 2002 Jul; 98 (1-2):151-61.
3. Langer M, et al. Neuropharmacology. 2011 Oct-Nov; 61 (5-6):1033-47.
2. Erichsen HK, et al. Pain. 2002 Jul; 98 (1-2):151-61.
3. Langer M, et al. Neuropharmacology. 2011 Oct-Nov; 61 (5-6):1033-47.
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Product Notes
The NS-1209 (Catalog #AAA3603709) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "NS-1209, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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