Structure
(Structure of S0096-25.)
SAPK2, p38 MAPK Inhibitor
SAPK2, p38 MAPK Inhibitor (SB 202190) (Stress-activated Protein Kinase 2)
Purity
Highly Purified98% (HPLC)
Synonyms
SAPK2; p38 MAPK Inhibitor; p38 MAPK Inhibitor (SB 202190) (Stress-activated Protein Kinase 2); inhibitor
Purity/Purification
Highly Purified
98% (HPLC)
98% (HPLC)
Form/Format
Supplied as a pale yellow solid.
Application Notes
Specific inhibitor of p38/SAPK2a MAPK and P38b/SAPK2a MAPK activity.
CAS Number
152121-30-7
Molecular Formula
C20H14FN3O
Solubility
Soluble in DMSO (50mg/ml).
Preparation and Storage
Stable for at least 12 months at -20 degree C in the dark. After reconstitution, aliquot and freeze at -20 degree C, away from light.
Structure
(Structure of S0096-25.)
Structure
(Structure of S0096-25.)
Related Product Information for SAPK2, p38 MAPK Inhibitor, inhibitor
SB 202190 is a cell permeable pyridinyl imidazole, which acts as a strong inhibitor of SAPK2a/p38 and SAPK2b/p38beta MAP kinases (IC50=280nM and 350nM, respectively). SB 202190 has no effect on the activity of the Erk or SAPK/JNK MAP kinases and is reported to block LPS induced TNF-a and IL-1beta production in mice. The compound is a slightly better inhibitor than the related compound SB 203580.
Product Categories/Family for SAPK2, p38 MAPK Inhibitor, inhibitor
Similar Products
Product Notes
The SAPK2, p38 MAPK Inhibitor (Catalog #AAA655445) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. Specific inhibitor of p38/SAPK2a MAPK and P38b/SAPK2a MAPK activity. Researchers should empirically determine the suitability of the SAPK2, p38 MAPK Inhibitor for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SAPK2, p38 MAPK Inhibitor, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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