MNKI-85, Inhibitor
MNKI-85
Purity
>98% (HPLC)
Synonyms
MNKI-85; MNKI85; inhibitor
Purity/Purification
>98% (HPLC)
Target
MNK
Receptor
MNK
Chemical Name
4-[[4-Fluoro-2-(1-methylethoxy)phenyl]amino]-N-(2-methoxyethyl)-5-methyl-thieno[2, 3-d]pyrimidine-6-carboxamide
Molecular Formula
C20H23FN4O3S
CAS Number
1812885-57-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Related Product Information for MNKI-85, inhibitor
MNKI-85 is a potent and selective Mnk2 inhibitor with Ki of 31nM, displays no inhibitory activities against Mnk1, CDK2A, CDK9T, and CDK4D; effectively inhibits the growth of AML cells that possess an M5 subtype with FLT3-internal tandem duplication mutation, a powerful pharmacologic tool in studying the Mnk2/eIF4E-mediated tumorigenic mechanism.
Product Categories/Family for MNKI-85, inhibitor
References
1. Teo T, et al. Mol Pharmacol. 2015 Aug; 88 (2):380-9.
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Product Notes
The MNKI-85 (Catalog #AAA3602783) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "MNKI-85, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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