Structure
LLL3, Inhibitor
LLL3
Purity
>98% (HPLC)
Synonyms
LLL3; LLL 3; inhibitor
Purity/Purification
>98% (HPLC)
Target
STAT
Receptor
STAT
Chemical Name
1-acetyl-5-hydroxyanthracene-9, 10-dione
SMILES
O=C(C1=C2C=CC=C1O)C3=CC=CC(C(C)=O)=C3C2=O
Molecular Formula
C16H10O4
CAS Number
63972-38-3
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for LLL3, inhibitor
LLL3 is a structural analogue of STA-21 that acts as a novel STAT3 inhibitor, inhibits STAT3-dependent transcriptional and DNA binding activities; also inhibits viability of U87, U373, and U251 glioblastoma cells as well as induces apoptosis of these glioblastoma cell lines; exhibits prolonged survival in U87 glioblastoma tumour-bearing mice.
Product Categories/Family for LLL3, inhibitor
References
1. Fuh B, et al. Br J Cancer. 2009 Jan 13; 100 (1):106-12.
2. Fossey SL, et al. BMC Cancer. 2009 Mar 10; 9:81.
3. Mencalha AL, et al. Cancer Chemother Pharmacol. 2010 May; 65 (6):1039-46.
2. Fossey SL, et al. BMC Cancer. 2009 Mar 10; 9:81.
3. Mencalha AL, et al. Cancer Chemother Pharmacol. 2010 May; 65 (6):1039-46.
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Product Notes
The LLL3 (Catalog #AAA3605428) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "LLL3, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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