Structure
Leelamine hydrochloride, Inhibitor
Leelamine hydrochloride
Purity
>98% (HPLC)
Synonyms
Leelamine hydrochloride; Dehydroabietylamine; inhibitor
Purity/Purification
>98% (HPLC)
Target
Androgen Receptor (AR)
Receptor
Androgen Receptor (AR)
Chemical Name
1R, 2, 3, 4, 4aS, 9, 10, 10aR-octahydro-1, 4a-dimethyl-7-(1-methylethyl)-1-phenanthrenemethanamine, monohydrochloride
SMILES
CC(C)C1=CC2=C(C=C1)C3(CCCC(C3CC2)(C)CN)C.Cl
Molecular Formula
C20H32ClN
CAS Number
16496-99-4
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Leelamine hydrochloride, inhibitor
Leelamine hydrochloride (Dehydroabietylamine) is a novel inhibitor of androgen receptor (AR), inhibits castration-resistant prostate cancer cells; causes apoptosis and suppresses 22Rv1 xenograft growth in vivo; Leelamine mediates cancer cell death through inhibition of intracellular cholesterol transport.
Product Categories/Family for Leelamine hydrochloride, inhibitor
References
1. Singh KB, et al. Mol Cancer Ther. 2018 Jul 20. pii: molcanther.0117.2018.
2. Gowda R, et al. Oncotarget. 2017 Apr 25; 8 (17):28260-28277.
3. Sehrawat A, et al. Mol Carcinog. 2017 Feb; 56 (2):337-348.
4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul; 13 (7):1690-703.
2. Gowda R, et al. Oncotarget. 2017 Apr 25; 8 (17):28260-28277.
3. Sehrawat A, et al. Mol Carcinog. 2017 Feb; 56 (2):337-348.
4. Kuzu OF, et al. Mol Cancer Ther. 2014 Jul; 13 (7):1690-703.
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Product Notes
The Leelamine hydrochloride (Catalog #AAA3602521) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Leelamine hydrochloride, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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