Structure
Enzalutamide Biochemical
Enzalutamide
Purity
>98% (HPLC)
Synonyms
Enzalutamide; MDV3100; MDV-3100; MDV 3100; Enzalutamide biochemical
Purity/Purification
>98% (HPLC)
Suitability
10mM in DMSO
Target
Androgen Receptor (AR)
Receptor
AndrogenReceptor
Chemical Name
Benzamide, 4-[3-[4-cyano-3-(trifluoromethyl)phenyl]-5, 5-dimethyl-4-oxo-2-thioxo-1-imidazolidinyl]-2-fluoro-N-methyl
SMILES
O=C(NC)C1=CC=C(N(C(N2C3=CC=C(C#N)C(C(F)(F)F)=C3)=S)C(C)(C)C2=O)C=C1F
Molecular Formula
C21H16F4N4O2S
CAS Number
915087-33-1
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Enzalutamide biochemical
An androgen-receptor (AR) antagonist with IC50 of 36nM; reduces the efficiency of AR nuclear translocation, and impairs both DNA binding to androgen response elements and recruitment of coactivators; induces tumor regression in mouse models of castration-resistant human prostate cancer; orally available. Prostate cancer Approved
Product Categories/Family for Enzalutamide biochemical
References
1. Tran C, et al. Science. 2009 May 8; 324 (5928):787-90.
2. Richards J, et al. Cancer Res. 2012 May 1; 72 (9):2176-82.
3. Scher HI, et al. N Engl J Med. 2012 Sep 27; 367 (13):1187-97.
2. Richards J, et al. Cancer Res. 2012 May 1; 72 (9):2176-82.
3. Scher HI, et al. N Engl J Med. 2012 Sep 27; 367 (13):1187-97.
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Product Notes
The Enzalutamide (Catalog #AAA3606567) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Enzalutamide, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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