Chemical Structure
KKI-5 acetate, Inhibitor | KKI-5, inhibitor
KKI-5 acetate (97145-43-2 free base)
Purity
0.9944
Synonyms
KKI-5 acetate; KKI-5 acetate (97145-43-2 free base); KKI-5; inhibitor
Purity/Purification
0.9944
Form/Format
Solid
Solubility
DMSO: 10mM
(<1mg/ml refers to the product slightly soluble or insoluble)
(<1mg/ml refers to the product slightly soluble or insoluble)
SMILES
CC([C@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H]1CCCN1C(C)=O)=O)CC2=CC=CC=C2)=O)CCC/N=C(N)\N)=O)CO)=O)C(N[C@H](C(N)=O)CCC(N)=O)=O)C.CC(O)=O
Formula
C37H59N11O11
In vitro
The KKI-5 Peptide corresponds to aa386-391 of bovine kininogen-1 that encompasses the aa388-389 kallikrein proteolytic site. The synthetic KKI-5 can attenuate breast cancer cell invasion, therefore it is investigated for its role in invasion and metastasis of cancer cells.
Preparation and Storage
Store at 0-4 degree C for short term (days to weeks), or -20 degree C for long term (months).
Chemical Structure
Chemical Structure
Related Product Information for KKI-5, inhibitor
KKI-5 acetate is a serine protease inhibitor that inhibits kallikrein and plasmin. KKI 5 may exhibit anticancer chemotherapeutic benefit and may also be used as a treatment for angioedema.
Product Categories/Family for KKI-5, inhibitor
References
Deshpande MS, et al. Mapping the binding site of tissue kallikrein: preparation and testing of all possible substrate analog inhibitors homologous with the sequence of kininogen between Ser386 and Gln392. J Med Chem. 1992 Aug 21;35(17):3094-102.
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Product Notes
The KKI-5 (Catalog #AAA5765459) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "KKI-5 acetate, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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