Structure
Kinetin riboside, Inhibitor
Kinetin riboside
Purity
>98% (HPLC)
Synonyms
Kinetin riboside; N6-Furfuryladenosine; FAdo; inhibitor
Purity/Purification
>98% (HPLC)
Suitability
DMSO: >=29mg/mL
Target
Apoptosis
Receptor
Apoptosis
Chemical Name
Adenosine, N-(2-furanylmethyl)
SMILES
O[C@H]1[C@H](N2C=NC3=C(NCC4=CC=CO4)N=CN=C23)O[C@H](CO)[C@H]1O
Molecular Formula
C15H17N5O5
CAS Number
4338-47-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for Kinetin riboside, inhibitor
A cytokinin analog that displays potent antiproliferative activity against various human cancer cell lines; inhibits MiPaCa-2 cell proliferation with IC50 of 0.27uM; induceds marked suppression of CCND2 transcription and rapidly suppresses cyclin D1 and D2 protein expression in primary myeloma cells and tumor lines, causing cell cycle arrest, tumor cell-selective apoptosis, and inhibition of myeloma growth in xenografted mice; also can activate PINK1 in cells independent of mitochondrial depolarization.
Product Categories/Family for Kinetin riboside, inhibitor
References
1. Osgerby L, et al. J Med Chem. 2017 Apr 27; 60 (8):3518-3524.
2. Tiedemann RE, et al. J Clin Invest. 2008 May; 118 (5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15; 154 (4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26; 285 (13):9770-9.
2. Tiedemann RE, et al. J Clin Invest. 2008 May; 118 (5):1750-64.
3. Hertz NT, et al. Cell. 2013 Aug 15; 154 (4):737-47.
4. Choi BH, et al. J Biol Chem. 2010 Mar 26; 285 (13):9770-9.
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Product Notes
The Kinetin riboside (Catalog #AAA3604475) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Kinetin riboside, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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