Structure

Hyperforin dicyclohexylammonium salt, Inhibitor

Hyperforin dicyclohexylammonium salt

Purity

98.00%

Synonyms

Hyperforin dicyclohexylammonium salt; Hyperforin DCHA; inhibitor

Ordering
Cat. Num. AAA5754974 For Research Use Only!

Purity/Purification

98.00%

Form/Format

Solid. Powder

Solubility

DMSO: 50mg/mL (69.63mM) Need ultrasonic
(<1mg/ml refers to the product slightly soluble or insoluble)

Formula

C47H75NO4

SMILES

CC(C)C([C@@]12[C@@](C)([C@H](C[C@](C/C=C(C)/C)(C(C(C/C=C(C)/C)=C2O)=O)C1=O)C/C=C(C)/C)CC/C=C(C)/C)=O.C3(CCCCC3)NC4CCCCC4

CAS Number

238074-03-8

Target & IC50

Others

In Vitro

Hyperforin dicyclohexylammonium salt shows a multi-directional mechanism of action. It also blocks the conductance of ligand-gated (GABA,nMDA, and AMPA receptors) and voltage-gated channels (Ca2+, K+, and Na+)[2].

Preparation and Storage

Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent

Structure

Related Product Information for Hyperforin dicyclohexylammonium salt, inhibitor

Hyperforin dicyclohexylammonium salt is a transient receptor canonical 6 channel activator with antidepressant effect. It modulates Ca2+ levels by activating Ca2+-conducting non-selective canonical TRPC6 channels.

References

Heiser JH, et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling. J Neurochem. 2013 Nov;127(3):303-13.
Heiser JH, et al. TRPC6 channel-mediated neurite outgrowth in PC12 cells and hippocampal neurons involves activation of RAS/MEK/ERK, PI3K, and CAMKIV signaling. J Neurochem. 2013 Nov;127(3):303-13.
Pochwat B, et al. Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice. Front Mol Neurosci. 2018 Dec 12;11:456.
Pochwat B, et al. Hyperforin Potentiates Antidepressant-Like Activity of Lanicemine in Mice. Front Mol Neurosci. 2018 Dec 12;11:456.

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Product Notes

The Hyperforin dicyclohexylammonium salt (Catalog #AAA5754974) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Hyperforin dicyclohexylammonium salt, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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Hyperforin dicyclohexylammonium salt, Inhibitor