Structure
ETX2514, Inhibitor
ETX2514
Purity
>98% (HPLC)
Synonyms
ETX2514; ETX 2514; ETX-2514; inhibitor
Purity/Purification
>98% (HPLC)
Target
Antibacterial
Receptor
Antibacterial
Chemical Name
sodium(2S, 5R)-2-carbamoyl-3-methyl-7-oxo-1, 6-diazabicyclo[3.2.1]oct-3-en-6-yl sulfate
SMILES
CC1=CC2CN(C1C(=O)N)C(=O)N2OS(=O)(=O)[O-].[Na+]
Molecular Formula
C8H10N3NaO6S
CAS Number
1467157-21-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for ETX2514, inhibitor
ETX2514 (ETX 2514, ETX-2514) is a covalent, broad-spectrum beta-lactamase inhibitor with IC50 of 4, 14 and 190nM for class A KPC-2, class C AmpC and class D OXA-24, respectively; potently inhibit clinically relevant class A, C and D beta-lactamases and penicillin-binding proteins, resulting in intrinsic antibacterial activity against Enterobacteriaceae and restoration of beta-lactam activity in a broad range of MDR Gram-negative pathogens; demonstrates potent antibacterial activity, in vivo efficacy against MDR A. baumannii infections combined with sulbactam. Bacterial Infection Phase 1 Clinical
Product Categories/Family for ETX2514, inhibitor
References
1. Durand-Rieville TF, et al. Nat Microbiol. 2017 Jun 30; 2:17104.
2. Shapiro AB, et al. ACS Infect Dis. 2017 Nov 10; 3 (11):833-844.
3. McLeod SM, et al. Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01576-17.
2. Shapiro AB, et al. ACS Infect Dis. 2017 Nov 10; 3 (11):833-844.
3. McLeod SM, et al. Antimicrob Agents Chemother. 2017 Nov 13. pii: AAC.01576-17.
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Product Notes
The ETX2514 (Catalog #AAA3602003) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "ETX2514, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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