Testing Data
()
Rabbit RANK Polyclonal Antibody | anti-RANK antibody
RANK antibody (HRP)
Gene Names
TNFRSF11A; FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1
Applications
ELISA, Immunohistochemistry, Western Blot
Purity
Purified by Ammonium Sulfate precipitation
Synonyms
RANK; Polyclonal Antibody; RANK antibody (HRP); Rabbit polyclonal RANK antibody (HRP); Polyclonal RANK antibody; Anti-RANK antibody; TNFRSF11A antibody; RANK antibody; Receptor activator of NF KB CD265 antibody; ODFR antibody; Osteoclast differentiation factor receptor antibody; anti-RANK antibody
Host
Rabbit
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Purified by Ammonium Sulfate precipitation
Form/Format
Supplied with 0.03% Proclin 300, 50% Glycerol and 0.01M PBS, PH 7.4
Sequence Length
616
Applicable Applications for anti-RANK antibody
ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB)
Immunogen
RANK antibody (HRP) was raised in Rabbit using recombinant human Tumor necrosis factor receptor superfamily member 11A protein as the immunogen
Conjugate
HRP
Cross-Reactivity
Human
Preparation and Storage
Store at 4 degree C for short term storage and-20 degree C for long term storage.
Avoid repeat freeze/thaw cycles.
Avoid repeat freeze/thaw cycles.
Testing Data
()
Testing Data
()
Related Product Information for anti-RANK antibody
The RANK/RANKL interaction is important in the regulation of osteoclastogenesis and in dendritic-cell-mediated T cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget disease of bone (PDB2). Recombinant human sRANK receptor is a 19.3 kDa polypeptide containing the TNFR homologous cysteine rich portion of the extracellular domain of RANK receptor (175 amino acid residues).
Product Categories/Family for anti-RANK antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
64,552 Da
NCBI Official Full Name
receptor activator of nuclear factor-kappa B
NCBI Official Synonym Full Names
TNF receptor superfamily member 11a
NCBI Official Symbol
TNFRSF11A
NCBI Official Synonym Symbols
FEO; OFE; ODFR; OSTS; PDB2; RANK; CD265; OPTB7; TRANCER; LOH18CR1
NCBI Protein Information
tumor necrosis factor receptor superfamily member 11A
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 11A
UniProt Gene Name
TNFRSF11A
UniProt Synonym Gene Names
RANK; ODFR
NCBI Description
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
Uniprot Description
Receptor for TNFSF11/RANKL/TRANCE/OPGL; essential for RANKL-mediated osteoclastogenesis. Involved in the regulation of interactions between T-cells and dendritic cells.
Research Articles on RANK
Similar Products
Product Notes
The RANK tnfrsf11a (Catalog #AAA5310124) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's RANK can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB). Researchers should empirically determine the suitability of the RANK tnfrsf11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RANK, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
