Structure
CPP-115, Inhibitor
CPP-115
Purity
>98% (HPLC)
Synonyms
CPP-115; CPP115; inhibitor
Purity/Purification
>98% (HPLC)
Target
GAT
Receptor
GAT
Chemical Name
(1S, 3S)-3-amino-4-(difluoromethylidene)cyclopentane-1-carboxylic acid
SMILES
O=C([C@@H]1C[C@H](N)/C(C1)=C(F)/F)O
Molecular Formula
C7H9F2NO2
CAS Number
640897-20-7
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for CPP-115, inhibitor
CPP-115 is an orally available, small molecule, next-generation GABA aminotransferase (GABA-AT) inhibitor with Ki of 31uM, without other GABAergic or off-target activities; displays superior enzyme inactivation properties compared to vigabatrin, decreases spasms in the multiple-hit rat model of infantile spasms, deonstrates high therapeutic potential for the treatment of cocaine addiction and for a variety of epilepsies.Epilepsy Phase 2 Clinical
Product Categories/Family for CPP-115, inhibitor
References
1. Pan Y, et al. J Med Chem. 2012 Jan 12; 55 (1):357-66.
2. Briggs SW, et al. Epilepsia. 2014 Jan; 55 (1):94-102.
3. Lee H, et al. J Am Chem Soc. 2015 Feb 25; 137 (7):2628-40.
4. Prescot AP, et al. Neuropsychopharmacology. 2018 Feb; 43 (3):646-654.
2. Briggs SW, et al. Epilepsia. 2014 Jan; 55 (1):94-102.
3. Lee H, et al. J Am Chem Soc. 2015 Feb 25; 137 (7):2628-40.
4. Prescot AP, et al. Neuropsychopharmacology. 2018 Feb; 43 (3):646-654.
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Product Notes
The CPP-115 (Catalog #AAA3605434) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CPP-115, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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