Cleomiscosin A, Inhibitor
Cleomiscosin A
Purity
98.00%
Synonyms
Cleomiscosin A; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C20H18O8
SMILES
COc(cc([C@H]([C@@H](CO)Oc1c(c(C=C2)c3)OC2=O)Oc1c3OC)cc1)c1O
CAS Number
76948-72-6
Target & IC50
LDL
TNF-alpha
TNF-alpha
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Related Product Information for Cleomiscosin A, inhibitor
Cleomiscosin A has antioxidant activity, it could be beneficial in preventing LDL oxidation in atherosclerotic lesions, it shows inhibitory activity to TNF-alpha+/- secretion of the mouse peritoneal macrophages.
Product Categories/Family for Cleomiscosin A, inhibitor
References
QSAR, docking and in vitro studies for anti-inflammatory activity of cleomiscosin A methyl ether derivatives.Eur J Pharm Sci. 2012 Dec 18;47(5):952-64.
QSAR, docking and in vitro studies for anti-inflammatory activity of cleomiscosin A methyl ether derivatives.Eur J Pharm Sci. 2012 Dec 18;47(5):952-64.
Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether.Eur J Med Chem. 2010 Nov;45(11):5150-6.
Chemical constituents from branch of Macaranga adenantha and their TNF-alpha inhibitory activity.Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(12):1175-9.
Antitumor Agents, 65. Brusatol and Cleomiscosin A, Antileukemic Principles from Brucea javanica.J Nat Prod. 1984 May-Jun;47(3):550-1.
QSAR, docking and in vitro studies for anti-inflammatory activity of cleomiscosin A methyl ether derivatives.Eur J Pharm Sci. 2012 Dec 18;47(5):952-64.
Synthesis and anti-inflammatory activity of derivatives of coumarino-lignoid, cleomiscosin A and its methyl ether.Eur J Med Chem. 2010 Nov;45(11):5150-6.
Chemical constituents from branch of Macaranga adenantha and their TNF-alpha inhibitory activity.Zhongguo Zhong Yao Za Zhi. 2007 Jun;32(12):1175-9.
Antitumor Agents, 65. Brusatol and Cleomiscosin A, Antileukemic Principles from Brucea javanica.J Nat Prod. 1984 May-Jun;47(3):550-1.
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Product Notes
The Cleomiscosin A (Catalog #AAA5760247) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Cleomiscosin A, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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