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Structure

CDK9-IN-4d, Inhibitor

CDK9-IN-4d

Purity
>98% (HPLC)
Synonyms
CDK9-IN-4d; inhibitor
Ordering
Purity/Purification
>98% (HPLC)
Target
CDK
Receptor
CDK
Chemical Name
N-(4-((7-cyclopentyl-6-(dimethylcarbamoyl)-7H-pyrrolo[2, 3-d]pyrimidin-2-yl)amino)phenyl)-N-(4-fluorophenyl)cyclopropane-1, 1-dicarboxamide
SMILES
FC1=CC=C(NC(C2(CC2)C(NC3=CC=C(NC4=NC=C5C(N(C6CCCC6)C(C(N(C)C)=O)=C5)=N4)C=C3)=O)=O)C=C1
Molecular Formula
C31H32FN7O3
CAS Number
2105956-51-0
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Structure

Structure
Related Product Information for CDK9-IN-4d, inhibitor
CDK9-IN-1 is a highly potent, selective CDK9 inhibitor with IC50 of 12nM, shows good selectivity in CDKs kinase profiling assay against CDK kinases and cell proliferation inhibition; blocks the cell cycle both in G0/G1 and G2/M phase to prevent the proliferation and differentiation of cancer cells; significantly suppresses cancer with low toxicity in mice bared-breast cancer.
Product Categories/Family for CDK9-IN-4d, inhibitor
References
1. Li Y, et al. Bioorg Med Chem Lett. 2017 Aug 1; 27 (15):3231-3237.

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Product Notes

The CDK9-IN-4d (Catalog #AAA3603347) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "CDK9-IN-4d, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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