Calcitriol D6, Inhibitor
Calcitriol D6
Purity
98.00%
Synonyms
Calcitriol D6; inhibitor
Purity/Purification
98.00%
Form/Format
Solid. Powder
Solubility
<1mg/ml refers to the product slightly soluble or insoluble
Formula
C27H38D6O3
SMILES
C=C1/C(C[C@H](C[C@@H]1O)O)=C\C=C2CCC[C@]3(C)[C@@H]([C@@H](CCCC(C([2H])([2H])[2H])(C([2H])([2H])[2H])O)C)CC[C@@]/23[H]
CAS Number
78782-99-7
Target & IC50
Others
Preparation and Storage
Store at -20 degree C for 3 years powder
-80 degree C for 2 years in solvent
-80 degree C for 2 years in solvent
Structure
Related Product Information for Calcitriol D6, inhibitor
Calcitriol D6 is the deuterated form of Calcitriol, which is the hormonally active form of vitamin D. Calcitriol is the active metabolite of vitamin D3 that activates the vitamin D receptor.
References
Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J. Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)
Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J. Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)
Calcitriol in cancer treatment, from the lab to the clinic. Mol.Cancer Ther. 3 373.
Calcitriol in cancer treatment, from the lab to the clinic. Mol.Cancer Ther. 3 373.
Nijenhuis et al (2006) The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 20 1589.
Nijenhuis et al (2006) The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 20 1589.
Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment, and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.
Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment, and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.
Alkharfy KM, Al-DaghrinM, Yakout SM, Ahmed M.Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model. Basic Clin Pharmacol Toxicol. 2012 Aug 21.
Alkharfy KM, Al-DaghrinM, Yakout SM, Ahmed M.Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model. Basic Clin Pharmacol Toxicol. 2012 Aug 21.
Canalejo et al (2000) The in vitro effect of calcitriol on parathyroid cell proliferation and apoptosis. J. Am.Soc.Nephrol. 11 1865. Beer and Myrthue (2004)
Calcitriol in cancer treatment, from the lab to the clinic. Mol.Cancer Ther. 3 373.
Calcitriol in cancer treatment, from the lab to the clinic. Mol.Cancer Ther. 3 373.
Nijenhuis et al (2006) The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 20 1589.
Nijenhuis et al (2006) The novel vitamin D analog ZK191784 as an intestine-specific vitamin D antagonist. FASEB J. 20 1589.
Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment, and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.
Krishnan AV, Swami S, Feldman D.Equivalent anticancer activities of dietary vitamin D and calcitriol in an animal model of breast cancer: Importance of mammary CYP27B1 for treatment, and prevention.J Steroid Biochem Mol Biol. 2012 Aug 23.
Alkharfy KM, Al-DaghrinM, Yakout SM, Ahmed M.Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model. Basic Clin Pharmacol Toxicol. 2012 Aug 21.
Alkharfy KM, Al-DaghrinM, Yakout SM, Ahmed M.Calcitriol Attenuates Weight-Related Systemic Inflammation and Ultrastructural Changes of the Liver in a Rodent Model. Basic Clin Pharmacol Toxicol. 2012 Aug 21.
