Structure
AZD 7009, Inhibitor
AZD 7009
Purity
>98% (HPLC)
Synonyms
AZD 7009; AZD7009; inhibitor
Purity/Purification
>98% (HPLC)
Target
Sodium Channel
Receptor
Sodium Channel
Chemical Name
tert-butyl N-[2-[3-[(2S)-3-(4-cyanophenoxy)-2-hydroxypropyl]-9-oxa-3, 7-diazabicyclo[3.3.1]nonan-7-yl]ethyl]carbamate
SMILES
N1(CC2OC(C1)CN(C2)CCNC(=O)OC(C)(C)C)C[C@@H](COc1ccc(C#N)cc1)O
Molecular Formula
C23H34N4O5
CAS Number
864368-79-6
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for AZD 7009, inhibitor
AZD 7009 is a novel antiarrhythmic agent that inhibits the late sodium current in CHO K1 cells expressing hNav1.5 with IC50 of 11uM; also inhibits late sodium current in isolated rabbit atrial and ventricular myocytes, attenuates the E-4031-induced action potential duration prolongation, induces early afterdepolarisations (EADs) in Purkinje fibres. Heart Arrhythmia Phase 2 Discontinued
Product Categories/Family for AZD 7009, inhibitor
References
1. Goldstein RN, et al. J Cardiovasc Electrophysiol. 2004 Dec; 15 (12):1444-50.
2. Persson F, et al. J Cardiovasc Electrophysiol. 2005 Mar; 16 (3):329-41.
3. Persson F, et al. J Cardiovasc Pharmacol. 2005 Jul; 46 (1):7-17.
4. Persson F, et al. Eur J Pharmacol. 2007 Mar 8; 558 (1-3):133-43.
2. Persson F, et al. J Cardiovasc Electrophysiol. 2005 Mar; 16 (3):329-41.
3. Persson F, et al. J Cardiovasc Pharmacol. 2005 Jul; 46 (1):7-17.
4. Persson F, et al. Eur J Pharmacol. 2007 Mar 8; 558 (1-3):133-43.
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Product Notes
The AZD 7009 (Catalog #AAA3606263) is an Inhibitor and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "AZD 7009, Inhibitor" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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