Mouse inner centromere protein antigens 135/155kDa ELISA Kit | INCENP elisa kit
Mouse Inner centromere protein, INCENP ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
INCENP: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. Probably acts through association with AURKB or AURKC. Seems to bind directly to microtubules. Controls the kinetochore localization of BUB1. Homodimer or heterodimer. Interacts with H2AFZ. Interacts with CBX3. Interacts with tubulin beta chain. Interacts with AURKB and AURKC. Component of the chromosomal passenger complex (CPC) composed of at least BIRC5/survivin, CDCA8/borealin, INCENP, AURKB and AURKC. Interacts with EVI5. Interacts with CDCA8 and BIRC5; interaction is direct. Interacts with CBX5; POGZ and INCENP compete for interaction with CBX5. Interacts with POGZ. Interacts with JTB. Belongs to the INCENP family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 2.7.11.1; Cell cycle regulation
Cellular Component: centric heterochromatin; microtubule; protein complex; chromosome; synaptonemal complex; kinetochore; lateral element; central element; cytoskeleton; cytoplasm; spindle; midbody; nucleus; chromosome, pericentric region; chromocenter
Biological Process: mitosis; cell division; cytokinesis; cell cycle; chromosome segregation
Research Articles on INCENP
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Product Notes
The Mouse INCENP incenp (Catalog #AAA9328480) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9328480 ELISA Kit recognizes Mouse INCENP. It is sometimes possible for the material contained within the vial of "inner centromere protein antigens 135/155kDa, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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