Human interleukin 4 induced 1 ELISA Kit | IL4I1 elisa kit

Human L-amino acid oxidase, LAO ELISA Kit

Cat. Num. AAA9316910

• Gene Names: IL4I1; LAO; FIG1; LAAO
• Reactivity: Human
• Synonyms: interleukin 4 induced 1; Human L-amino acid oxidase; LAO ELISA Kit; Human L-amino acid oxidase (LAO) ELISA Kit; FIG1; Fig-1 protein; interleukin 4 induced protein 1; interleukin four induced 1; IL4I1 elisa kit

• Reactivity: Human
• Specificity: No significant cross-reactivity or interference between this analyte and analogues is observed.

• Samples: Body fluids, tissue homogenates, secretions or feces samples
• Assay Type: Quantitative Sandwich
• Detection Range: 0.625 ng/ml - 20 ng/ml
• Sensitivity: 0.1 ng/ml.
• Intra-assay Precision: Intra-assay CV (%) is less than 15%
• Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
• Preparation and Storage: Store all reagents at 2-8 degree C

Related Product Information for IL4I1 elisa kit

Background/Introduction: This Quantitative Sandwich ELISA kit is only for in vitro research use only! This kit is intended to be used for determination the level of LAO (hereafter termed "analyte") in undiluted original Human body fluids, tissue homogenates, secretions or feces samples. This kit is NOT suitable for assaying non-biological sources of substances.

NCBI and Uniprot Product Information

• NCBI GI #: 384381475
• NCBI GeneID: 259307
• NCBI Accession #: NP_001244946.1
• NCBI GenBank Nucleotide #: NM_001258017.1
• UniProt Accession #: Q96RQ9; Q1WMJ3; Q4GZN1; Q4GZN2; Q6P2Q3; Q8TEM5; Q96RQ8
• Molecular Weight: 62,881 Da
• NCBI Official Full Name: L-amino-acid oxidase isoform 2
• NCBI Official Synonym Full Names: interleukin 4 induced 1
• NCBI Official Symbol: IL4I1
• NCBI Official Synonym Symbols: LAO; FIG1; LAAO
• NCBI Protein Information: L-amino-acid oxidase; Fig-1 protein; IL4-induced protein 1; interleukin four induced 1
• UniProt Protein Name: L-amino-acid oxidase
• UniProt Gene Name: IL4I1
• UniProt Synonym Gene Names: FIG1; UNQ636/PRO1265; LAAO; LAO; IL4-induced protein 1; hFIG1
• UniProt Entry Name: OXLA_HUMAN

NCBI Description

This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Uniprot Description

IL4I1: Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. 2 isoforms of the human protein are produced by alternative promoter.

Protein type: Oxidoreductase; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Secreted; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - cysteine and methionine; Amino Acid Metabolism - tyrosine; Amino Acid Metabolism - phenylalanine; Amino Acid Metabolism - alanine, aspartate and glutamate; Secreted, signal peptide; EC 1.4.3.2

Chromosomal Location of Human Ortholog: 19q13.3-q13.4

Cellular Component: lysosome; extracellular region

Molecular Function: L-amino-acid oxidase activity