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IL4I1 cdna clone
IL4I1 cDNA Clone
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NCBI and Uniprot Product Information
NCBI Description
This gene encodes a protein with limited similarity to L-amino acid oxidase which contains the conserved amino acids thought to be involved in catalysis and binding of flavin adenine dinucleotide (FAD) cofactor. The expression of this gene can be induced by interleukin 4 in B cells, however, expression of transcripts containing the first two exons of the upstream gene is found in other cell types. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
Uniprot Description
IL4I1: Lysosomal L-amino-acid oxidase with highest specific activity with phenylalanine. May play a role in lysosomal antigen processing and presentation. Belongs to the flavin monoamine oxidase family. FIG1 subfamily. 2 isoforms of the human protein are produced by alternative promoter.
Protein type: Amino Acid Metabolism - valine, leucine and isoleucine degradation; Amino Acid Metabolism - alanine, aspartate and glutamate; Amino Acid Metabolism - phenylalanine, tyrosine and tryptophan biosynthesis; Amino Acid Metabolism - cysteine and methionine; Oxidoreductase; Amino Acid Metabolism - tryptophan; Amino Acid Metabolism - phenylalanine; Secreted, signal peptide; EC 1.4.3.2; Secreted; Amino Acid Metabolism - tyrosine
Chromosomal Location of Human Ortholog: 19q13.3-q13.4
Cellular Component: lysosome; extracellular region
Molecular Function: L-amino-acid oxidase activity
Research Articles on IL4I1
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Product Notes
The IL4I1 il4i1 (Catalog #AAA1270935) is a cDNA Clone and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ATGGCCCCAT TGGCCCTGCA CCTCCTCGTC CTCGTCCCCA TCCTCCTCAG CCTGGTGGCC TCCCAGGACT GGAAGGCTGA ACGCAGCCAA GACCCCTTCG AGAAATGCAT GCAGGATCCT GACTATGAGC AGCTGCTCAA GGTGGTGACC TGGGGGCTCA ATCGGACCCT GAAGCCCCAG AGGGTGATTG TGGTTGGCGC TGGTGTGGCC GGGCTGGTGG CCGCCAAGGT GCTCAGCGAT GCTGGACACA AGGTCACCAT CCTGGAGGCA GATAACAGGA TCGGGGGCCG CATCTTCACC TACCGGGACC AGAACACGGG CTGGATTGGG GAGCTGGGAG CCATGCGCAT GCCCAGCTCT CACAGGATCC TCCACAAGCT CTGCCAGGGC CTGGGGCTCA ACCTGACCAA GTTCACCCAG TACGACAAGA ACACGTGGAC GGAGGTGCAC GAAGTGAAGC TGCGCAACTA TGTGGTGGAG AAGGTGCCCG AGAAGCTGGG CTACGCCTTG CGTCCCCAGG AAAAGGGCCA CTCGCCCGAA GACATCTACC AGATGGCTCT CAACCAGGCC CTCAAAGACC TCAAGGCACT GGGCTGCAGA AAGGCGATGA AGAAGTTTGA AAGGCACACG CTCTTGGAAT ATCTTCTCGG GGAGGGGAAC CTGAGCCGGC CGGCCGTGCA GCTTCTGGGA GACGTGATGT CCGAGGATGG CTTCTTCTAT CTCAGCTTCG CCGAGGCCCT CCGGGCCCAC AGCTGCCTCA GCGACAGACT CCAGTACAGC CGCATCGTGG GTGGCTGGGA CCTGCTGCCG CGCGCGCTGC TGAGCTCGCT GTCCGGGCTT GTGCTGTTGA ACGCGCCCGT GGTGGCGATG ACCCAGGGAC CGCACGATGT GCACGTGCAG ATCGAGACCT CTCCCCCGGC GCGGAATCTG AAGGTGCTGA AGGCCGACGT GGTGCTGCTG ACGGCGAGCG GACCGGCGGT GAAGCGCATC ACCTTCTCGC CGCCGCTGCC CCGCCACATG CAGGAGGCGC TGCGGAGGCT GCACTACGTG CCGGCCACCA AGGTGTTCCT AAGCTTCCGC AGGCCCTTCT GGCGCGAGGA GCACATTGAA GGCGGCCACT CAAACACCGA TCGCCCGTCG CGCATGATTT TCTACCCGCC GCCGCGCGAG GGCGCGCTGC TGCTGGCCTC GTACACGTGG TCGGACGCGG CGGCAGCGTT CGCCGGCTTG AGCCGGGAAG AGGCGTTGCG CTTGGCGCTC GACGACGTGG CGGCATTGCA CGGGCCTGTC GTGCGCCAGC TCTGGGACGG CACCGGCGTC GTCAAGCGTT GGGCGGAGGA CCAGCACAGC CAGGGTGGCT TTGTGGTACA GCCGCCGGCG CTCTGGCAAA CCGAAAAGGA TGACTGGACG GTCCCTTATG GCCGCATCTA CTTTGCCGGC GAGCACACCG CCTACCCGCA CGGCTGGGTG GAGACGGCGG TCAAGTCGGC GCTGCGCGCC GCCATCAAGA TCAACAGCCG GAAGGGGCCT GCATCGGACA CGGCCAGCCC CGAGGGGCAC GCATCTGACA TGGAGGGGCA GGGGCATGTG CATGGGGTGG CCAGCAGCCC CTCGCATGAC CTGGCAAAGG AAGAAGGCAG CCACCCTCCA GTCCAAGGCC AGTTATCTCT CCAAAACACG ACCCACACGA GGACCTCGCA TTAA. It is sometimes possible for the material contained within the vial of "IL4I1, cDNA Clone" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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