Typical Testing Data/Standard Curve
Mouse IL-20 ELISA Kit | IL20 elisa kit
Mouse IL-20 ELISA Kit
Gene Names
Il20; Zcyto10
Reactivity
Mouse
Applications
ELISA
Synonyms
IL-20; Mouse IL-20 ELISA Kit; ZCYTO10; Interleukin-20; Cytokine Zcyto10; IL20 elisa kit
Reactivity
Mouse
Specificity
The Mouse IL-20 ELISA Kit allows for the detection and quantification of endogenous levels of natural and/or recombinant Mouse IL-20 proteins within the range of 31.2 pg/ml - 2000 pg/ml.
Sequence Length
176
Applicable Applications for IL20 elisa kit
Sandwich ELISA (EIA)
Samples
Cell Culture Supernatants, Serum, Plasma.
Sensitivity
10 pg/ml.
Preparation and Storage
Shipped and store at 4 degree C for 6 months, store at -20 degree C for one year. Avoid freeze/thaw cycles.
Typical Testing Data/Standard Curve
Typical Testing Data/Standard Curve
Related Product Information for IL20 elisa kit
Principle of the Assay||The Mouse IL-20 ELISA (Enzyme-Linked Immunosorbent Assay) kit is an in vitro enzyme-linked immunosorbent assay for the quantitative measurement of Mouse IL-20 in Cell Culture Supernatants, Serum, Plasma. This assay employs an antibody specific for Mouse IL-20 coated on a 96-well plate. Standards and samples are pipetted into the wells and IL-20 present in a sample is bound to the wells by the immobilized antibody. The wells are washed and biotinylated anti-Mouse IL-20 antibody is added. After washing away unbound biotinylated antibody, HRP-conjugated streptavidin is pipetted to the wells. The wells are again washed, a TMB substrate solution is added to the wells and color develops in proportion to the amount of IL-20 bound. The Stop Solution changes the color from blue to yellow, and the intensity of the color is measured at 450 nm.
Background/Introduction: IL-20, also known as Interleukin 20 or Zcyto10, is a protein that in humans is encoded by the IL20 gene. This gene is mapped to 1q32.1. IL-20 is a protein belonging to the IL-10 family of cytokines. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.
Background/Introduction: IL-20, also known as Interleukin 20 or Zcyto10, is a protein that in humans is encoded by the IL20 gene. This gene is mapped to 1q32.1. IL-20 is a protein belonging to the IL-10 family of cytokines. This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is found to be expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis. IL-20 regulates proliferation and differentiation of keratinocytes during inflammation, particularly inflammation associated with the skin. In addition, IL-20 also causes cell expansion of multipotential hematopoietic progenitor cells.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
UniProt Accession #
Molecular Weight
20,098 Da
NCBI Official Full Name
Interleukin-20
NCBI Official Synonym Full Names
interleukin 20
NCBI Official Symbol
Il20
NCBI Official Synonym Symbols
Zcyto10
NCBI Protein Information
interleukin-20
UniProt Protein Name
Interleukin-20
Protein Family
UniProt Gene Name
Il20
UniProt Synonym Gene Names
Zcyto10; IL-20
UniProt Entry Name
IL20_MOUSE
Uniprot Description
IL20: Cytokine that may be involved in epidermal function and psoriasis. Acts through STAT3. Belongs to the IL-10 family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Cellular Component: extracellular region; extracellular space
Molecular Function: cytokine activity; interleukin-20 receptor binding; interleukin-22 receptor binding; receptor binding
Biological Process: hemopoiesis; immune response; inflammatory response; positive regulation of JAK-STAT cascade; positive regulation of osteoclast differentiation; STAT protein nuclear translocation
Research Articles on IL20
Similar Products
Product Notes
The Mouse IL20 il20 (Catalog #AAA8244610) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA8244610 ELISA Kit recognizes Mouse IL20. AAA Biotech's IL-20 can be used in a range of immunoassay formats including, but not limited to, Sandwich ELISA (EIA). Researchers should empirically determine the suitability of the IL20 il20 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL-20, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
