IL-1 Receptor-Like 2/IL-1RL2/IL-1Rrp2/IL-36R Recombinant Protein | IL-1 recombinant protein

Recombinant Mouse IL-1 Receptor-Like 2/IL-1RL2/IL-1Rrp2/IL-36R (C-Fc)

Cat. Num. AAA2569327

• Gene Names: Il1rl2; AI481289; AW551444; IL-1Rrp2
• Purity: >95% as determined by reducing SDS-PAGE
• Synonyms: IL-1 Receptor-Like 2/IL-1RL2/IL-1Rrp2/IL-36R; Recombinant Mouse IL-1 Receptor-Like 2/IL-1RL2/IL-1Rrp2/IL-36R (C-Fc); Interleukin-1 receptor-like 2; IL1RL2; IL-36 receptor; IL-36R; IL-1Rrp2; IL1R-rp2; IL-1 recombinant protein

• Host: Human Cells
• Purity/Purification: >95% as determined by reducing SDS-PAGE
• Form/Format: Lyophilized from a 0.2um filtered solution of PBS, pH7.4.
• Sequence: Asp22-Arg338(Ala158Val)

• Species: Mouse
• Tag: C-Fc
• Endotoxin: <1.0EU per ug as determined by the LAL method.
• Protein Construction: Recombinant Mouse Interleukin-1 Receptor-like 2 is produced by our Mammalian expression system and the target gene encoding Asp22-Arg338(Ala158Val) is expressed with a Fc tag at the C-terminus.
• Preparation and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80 degree C. Reconstituted protein solution can be stored at 4-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at < -20 degree C for 3 months.; This product is provided as lyophilized powder which is shipped with ice packs.

SDS-Page

Related Product Information for IL-1 recombinant protein

Interleukin-1 receptor-like 2 is a protein that in humans is encoded by the IL1RL2 gene, belongs to the interleukin-1 receptor family.IL1RL2 is the receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

NCBI and Uniprot Product Information

• NCBI GI #: 18875334
• NCBI GeneID: 107527
• NCBI Accession #: NP_573456.1
• NCBI GenBank Nucleotide #: NM_133193.3
• UniProt Accession #: Q9ERS7
• Molecular Weight: 65,108 Da
• NCBI Official Full Name: interleukin-1 receptor-like 2
• NCBI Official Synonym Full Names: interleukin 1 receptor-like 2
• NCBI Official Symbol: Il1rl2
• NCBI Official Synonym Symbols: AI481289; AW551444; IL-1Rrp2
• NCBI Protein Information: interleukin-1 receptor-like 2; IL1R-rp2; IL-36 receptor; interleukin-1 receptor related protein 2; interleukin-1 receptor-related protein 2
• UniProt Protein Name: Interleukin-1 receptor-like 2
• UniProt Gene Name: Il1rl2
• UniProt Synonym Gene Names: IL-1Rrp2; IL1R-rp2
• UniProt Entry Name: ILRL2_MOUSE

Uniprot Description

IL1RL2: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral

Cellular Component: membrane; integral to membrane

Molecular Function: interleukin-1, Type I, activating receptor activity; hematopoietin/interferon-class (D200-domain) cytokine receptor activity; interleukin-1 receptor activity

Biological Process: positive regulation of T cell differentiation; immune system process; cytokine and chemokine mediated signaling pathway; regulation of inflammatory response; positive regulation of interleukin-6 production; innate immune response; inflammatory response; signal transduction