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Immunohistochemistry (IHC) (Anti-IL1RL2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Rabbit IL1RL2 Polyclonal Antibody | anti-IL1RL2 antibody

Anti-IL1RL2 Antibody (Internal) IHC-plus

Gene Names
IL1RL2; IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2
Reactivity
Mouse, Rat, Human
Applications
Immunohistochemistry, Immunofluorescence, Western Blot, ELISA
Purity
Immunoaffinity purified
Synonyms
IL1RL2; Polyclonal Antibody; Anti-IL1RL2 Antibody (Internal) IHC-plus; Rabbit Polyclonal (IgG) to Human IL1RL2; Human IL1RL2; IL-1Rrp2; IL1R-rp2; IL1RRP2; Interleukin 1 receptor-like 2; Interleukin-1 receptor-like 2; IL-36R; anti-IL1RL2 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse, Rat, Human
Clonality
Polyclonal
Isotype
IgG
Specificity
IL-1RL2 antibody is human, mouse and rat reactive. At least three isoforms of IL-1RL2 are known to exist; this antibody will detect all three isoforms. IL-1RL2 antibody is predicted to not cross-react with IL-1R or IL-1RL1.
Purity/Purification
Immunoaffinity purified
Form/Format
PBS, 0.02% sodium azide.
Concentration
1 mg/ml (varies by lot)
Sequence Length
575
Applicable Applications for anti-IL1RL2 antibody
Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA)
Application Notes
IF (20 ug/ml)
IHC-P (10 ug/ml)
WB (1 - 2 ug/ml)
Immunogen
IL1RL2 antibody was raised against 16 amino acid peptide near the center of human IL-1RL2.
Immunogen Description
16 amino acid peptide near the center of human IL-1RL2.
Antigen Modification
Internal
Target Species
Human
Preparation and Storage
Long term: -20 degree C
Short term: 4 degree C
Avoid repeat freeze-thaw cycles

Immunohistochemistry (IHC)

(Anti-IL1RL2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunohistochemistry (IHC) (Anti-IL1RL2 antibody IHC staining of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 20 ug/ml.)

Immunofluorescence (IF) (Immunofluorescence of IL-1RL2 in human small intestine tissue with IL-1RL2 antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot analysis of IL-1RL2 in human small intestine lysate with IL-1RL2 antibody at (A) 1 and (B) 2 ug/ml.)

Western Blot (WB) (Western blot analysis of IL-1RL2 in human small intestine lysate with IL-1RL2 antibody at (A) 1 and (B) 2 ug/ml.)
Related Product Information for anti-IL1RL2 antibody
IL1RL2 Antibody, IL-1Rrp2 Antibody, IL1R-rp2 Antibody, IL1RRP2 Antibody, Interleukin 1 receptor-like 2 Antibody, Interleukin-1 receptor-like 2 Antibody, IL-36R Antibody Description: Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
51,658 Da
NCBI Official Full Name
interleukin-1 receptor-like 2
NCBI Official Synonym Full Names
interleukin 1 receptor like 2
NCBI Official Symbol
IL1RL2
NCBI Official Synonym Symbols
IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2
NCBI Protein Information
interleukin-1 receptor-like 2
UniProt Protein Name
Interleukin-1 receptor-like 2
Protein Family
UniProt Gene Name
IL1RL2
UniProt Synonym Gene Names
IL1RRP2; IL-36R; IL-1Rrp2; IL1R-rp2
UniProt Entry Name
ILRL2_HUMAN

NCBI Description

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]

Uniprot Description

IL1RL2: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12

Cellular Component: integral to plasma membrane

Molecular Function: interleukin-1 receptor activity; interleukin-1, Type I, activating receptor activity

Biological Process: cellular defense response; cytokine and chemokine mediated signaling pathway; inflammatory response; innate immune response; positive regulation of interleukin-6 production; positive regulation of T cell differentiation; regulation of inflammatory response; signal transduction

Research Articles on IL1RL2

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Product Notes

The IL1RL2 il1rl2 (Catalog #AAA249599) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-IL1RL2 Antibody (Internal) IHC-plus reacts with Mouse, Rat, Human and may cross-react with other species as described in the data sheet. AAA Biotech's IL1RL2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Immunofluorescence (IF), Western Blot (WB), ELISA (EIA). IF (20 ug/ml) IHC-P (10 ug/ml) WB (1 - 2 ug/ml). Researchers should empirically determine the suitability of the IL1RL2 il1rl2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "IL1RL2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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