Il17rb recombinant protein

Il17rb, 18-286aa, Mouse, hIgG-His-tag, Baculovirus

Cat. Num. AAA206479

• Gene Names: Il17rb; Evi27; Il17br; IL-17ER; IL17RH1; IL-17Rh1
• Applications: SDS-Page
• Purity: > 90% by SDS-PAGE
• Synonyms: Il17rb; 18-286aa; Mouse; hIgG-His-tag; Baculovirus; Interleukin-17 receptor B; Evi27; IL-17ER; IL-17Rh1; Il17br; IL17RH1; Il17rb recombinant protein

• Host: Baculovirus
• Purity/Purification: > 90% by SDS-PAGE
• Form/Format: Liquid. In phosphate buffered saline (pH 7.4) containing 10% glycerol.
• Concentration: 1mg/ml (determined by Absorbance at 280nm) (varies by lot)
• Sequence: ADPREPTIQC GSETGPSPEW MVQHTLTPGD LRDLQVELVK TSVAAEEFSI LMNISWILRA DASIRLLKAT KICVSGKNNM NSYSCVRCNY TEAFQSQTRP SGGKWTFSYV GFPVELSTLY LISAHNIPNA NMNEDSPSLS VNFTSPGCLN HVMKYKKQCT EAGSLWDPDI TACKKNEKMV EVNFTTNPLG NRYTILIQRD TTLGFSRVLE NKLMRTSVAI PVTEESEGAV VQLTPYLHTC GNDCIRREGT VVLCSETSAP IPPDDNRRML GGVEPKSCDK THTCPPCPAP ELLGGPSVFL FPPKPKDTLM ISRTPEVTCV VVDVSHEDPE VKFNWYVDGV EVHNAKTKPR EEQYNSTYRV VSVLTVLHQD WLNGKEYKCK VSNKALPAPI EKTISKAKGQ PREPQVYTLP PSRDELTKNQ VSLTCLVKGF YPSDIAVEWE SNGQPENNYK TTPPVLDSDG SFFLYSKLTV DKSRWQQGNV FSCSVMHEAL HNHYTQKSLS LSPGKHHHHH H
• Sequence Length: 499

• Applicable Applications for Il17rb recombinant protein: SDS-PAGE
• Antigen Species: Mouse
• Tag Information: hIgG-His-tag
• Endotoxin Level: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Preparation and Storage: Can be stored at 4 degree C short term (1-2 weeks).; For long term storage, aliquot and store at -20 degree C or -70 degree C.; Avoid repeated freezing and thawing cycles.

SDS-Page

Related Product Information for Il17rb recombinant protein

Il17rb, also known as Interleukin-17 receptor B, is a cytokine receptor. This receptor specifically binds to IL17B and IL17E (IL25), but does not bind to IL17 (A) or IL17C. It has been shown to mediate the activation of NF- kB and the production of IL8 induced by IL17E. It was found to be significantly up-regulated during intestinal inflammation, which suggested the immune regulatory activity of this receptor. Recombinant mouse Il17rb, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Product Categories/Family for Il17rb recombinant protein

Immunology

References

Rickel EA. et al., (2008) J. Immunol. 181 (6):4299-4310.; Aggarwal, S. et al., (2002) J. Leukoc. Biol. 71:1-8.

NCBI and Uniprot Product Information

• NCBI GI #: 83025064
• NCBI GeneID: 50905
• NCBI Accession #: NP_062529
• NCBI GenBank Nucleotide #: NM_019583.3
• UniProt Accession #: Q9JIP3; Q9JIP2
• Molecular Weight: 57.1kDa (511aa) 57-70KDa (SDS-PAGE under reducing conditions.)
• NCBI Official Full Name: interleukin-17 receptor B
• NCBI Official Synonym Full Names: interleukin 17 receptor B
• NCBI Official Symbol: Il17rb
• NCBI Official Synonym Symbols: Evi27; Il17br; IL-17ER; IL17RH1; IL-17Rh1
• NCBI Protein Information: interleukin-17 receptor B
• UniProt Protein Name: Interleukin-17 receptor B
• Protein Family: Interleukin-17 receptor
• UniProt Gene Name: Il17rb
• UniProt Synonym Gene Names: Evi27; Il17br; IL-17 receptor B; IL-17RB; IL-17ER; IL-17Rh1; IL17Rh1; IL-17B receptor

Uniprot Description

Receptor for the proinflammatory cytokines IL17B and IL17E. May play a role in controlling the growth and/or differentiation of hematopoietic cells.