Interleukin 15 (IL15) Recombinant Protein | IL15 recombinant protein

Recombinant Interleukin 15 (IL15)

Cat. Num. AAA2009546

• Gene Names: Il15; IL-15; AI503618
• Applications: SDS-Page, Western Blot, ELISA, Immunoprecipitation
• Purity: > 97%
• Synonyms: Interleukin 15 (IL15); Recombinant Interleukin 15 (IL15); IL15 recombinant protein

• Host: E Coli
• Purity/Purification: > 97%
• Form/Format: Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Sequence: The target protein is fused with a N-terminal His-tag, its sequence is listed below.; MGHHHHHHSGSEF-NW IDVRYDLEKI ESLIQSIHID TTLYTDSDFH PSCKVTAMNC FLLELQVILH EYSNMTLNET VRNVLYLANS TLSSNKNVAE SGCKECEELE EKTFTEFLQS FIRIVQMFIN TS
• Sequence Length: 162

• Applicable Applications for IL15 recombinant protein: SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
• Organism: Mus musculus (Mouse)
• Expression System: Prokaryotic expression
• Residues: Asn49~ Ser162 (Accession # P48346) with a N-terminal His-tag
• Endotoxin Level: <1.0EU per 1ug (determined by the LAL method)
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Preparation and Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.; Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

SDS-Page

NCBI and Uniprot Product Information

• NCBI GI #: 363000984
• NCBI GeneID: 16168
• NCBI Accession #: NP_001241676.1
• NCBI GenBank Nucleotide #: NM_001254747.1
• UniProt Accession #: P48346
• Molecular Weight: 14.7kDa
• NCBI Official Full Name: interleukin-15
• NCBI Official Synonym Full Names: interleukin 15
• NCBI Official Symbol: Il15
• NCBI Official Synonym Symbols: IL-15; AI503618
• NCBI Protein Information: interleukin-15
• UniProt Protein Name: Interleukin-15
• Protein Family: Interleukin
• UniProt Gene Name: Il15
• UniProt Synonym Gene Names: IL-15
• UniProt Entry Name: IL15_MOUSE

Uniprot Description

IL15: Cytokine that stimulates the proliferation of T- lymphocytes. Stimulation by IL-15 requires interaction of IL-15 with components of IL-2R, including IL-2R beta and probably IL-2R gamma but not IL-2R alpha. Belongs to the IL-15/IL-21 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted, signal peptide; Cell cycle regulation; Secreted; Cytokine

Cellular Component: nucleoplasm; extracellular space; cell surface; cytoplasm; extracellular region

Molecular Function: hematopoietin/interferon-class (D200-domain) cytokine receptor binding; cytokine activity

Biological Process: positive regulation of interleukin-17 production; positive regulation of immune response; NK T cell proliferation; positive regulation of natural killer cell proliferation; negative regulation of smooth muscle cell proliferation; cell maturation; signal transduction; lymph node development; positive regulation of tyrosine phosphorylation of Stat3 protein; positive regulation of natural killer cell differentiation; extrathymic T cell selection; natural killer cell differentiation; positive regulation of cell proliferation; positive regulation of T cell proliferation; regulation of T cell differentiation; immune response; regulation of defense response to virus by host; hyaluronan metabolic process