Rat Insulin-like growth factor-binding protein 3 ELISA Kit | Igfbp3 elisa kit
Rat Insulin-like growth factor-binding protein 3 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
an insulin growth factor (Igf) binding protein; involved in modulating IGF-I action [RGD, Feb 2006]
Uniprot Description
IGFBP3: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.
Protein type: Cell development/differentiation; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; nuclear heterochromatin; nucleus
Molecular Function: fibronectin binding; insulin-like growth factor binding; insulin-like growth factor I binding; insulin-like growth factor II binding; protein binding; protein tyrosine phosphatase activator activity
Biological Process: aging; negative regulation of cell proliferation; negative regulation of protein amino acid phosphorylation; negative regulation of smooth muscle cell migration; negative regulation of smooth muscle cell proliferation; osteoblast differentiation; positive regulation of apoptosis; positive regulation of catalytic activity; positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of MAPKKK cascade; positive regulation of myoblast differentiation; protein amino acid phosphorylation; regulation of cell growth; regulation of growth; regulation of insulin-like growth factor receptor signaling pathway
Research Articles on Igfbp3
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Product Notes
The Rat Igfbp3 igfbp3 (Catalog #AAA289488) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA289488 ELISA Kit recognizes Rat Igfbp3. It is sometimes possible for the material contained within the vial of "Insulin-like growth factor-binding protein 3, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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