Western Blot (WB)
(Anti-Kallikrein 11 antibody, MBS175534, Western blottingAll lanes: Anti Kallikrein 11 (MBS175534) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: MM231 Whole Cell Lysate at 40ugLane 5: MM453 Whole Cell Lysate at 40ugLane 6: COLO320 Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 31KDObserved bind size: 31KD )
Rabbit anti-Human Kallikrein 11 Polyclonal Antibody | anti-KLK11 antibody
Anti-Kallikrein 11 antibody
Western Blot (WB)
(Anti-Kallikrein 11 antibody, MBS175534, Western blottingAll lanes: Anti Kallikrein 11 (MBS175534) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: MM231 Whole Cell Lysate at 40ugLane 5: MM453 Whole Cell Lysate at 40ugLane 6: COLO320 Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 31KDObserved bind size: 31KD )
Western Blot (WB)
(Anti-Kallikrein 11 antibody, MBS175534, Western blottingAll lanes: Anti Kallikrein 11 (MBS175534) at 0.5ug/mlLane 1: U87 Whole Cell Lysate at 40ugLane 2: A549 Whole Cell Lysate at 40ugLane 3: HELA Whole Cell Lysate at 40ugLane 4: MM231 Whole Cell Lysate at 40ugLane 5: MM453 Whole Cell Lysate at 40ugLane 6: COLO320 Whole Cell Lysate at 40ugLane 7: JURKAT Whole Cell Lysate at 40ugPredicted bind size: 31KDObserved bind size: 31KD )
Immunohistochemistry (IHC)
(Anti-Kallikrein 11 antibody, MBS175534, IHC(P)IHC(P): Human Prostatic Cancer Tissue )
Immunohistochemistry (IHC)
(Anti-Kallikrein 11 antibody, MBS175534, IHC(P)IHC(P): Human Prostatic Cancer Tissue )
Background: KLK11(KALLIKREIN 11), also called PRSS20 or TLSP, is a protein that in humans is encoded by the KLK11 gene. KLK11 is a member of the kallikrein subfamily of serine proteases, which are involved in a variety of enzymatic processes. The KLK11 gene is mapped to 19q13.41. The KLK11 gene contains 6 exons, the first of which is noncoding. KLK11 shares 48% amino acid sequence identity with mouse neuropsin, 43% identity with both human trypsin-1 and human kallikrein, and 38% identity with the mouse nerve growth factor gamma subunit. Alternate splicing of the KLK11 gene results in two transcript variants encoding two different isoforms which are differentially expressed. Western blot analysis of recombinant KLK11 suggested that the protein is secreted and posttranslationally processed.
NCBI and Uniprot Product Information
NCBI Description
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms which are differentially expressed.[provided by RefSeq, Nov 2009]
Uniprot Description
KLK11: Possible multifunctional protease. Efficiently cleaves 'bz-Phe-Arg-4-methylcoumaryl-7-amide', a kallikrein substrate, and weakly cleaves other substrates for kallikrein and trypsin. Cleaves synthetic peptides after arginine but not lysine residues. Belongs to the peptidase S1 family. Kallikrein subfamily. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Protease; EC 3.4.21.-; Secreted
Chromosomal Location of Human Ortholog: 19q13.33
Cellular Component: Golgi apparatus; extracellular space
Molecular Function: serine-type peptidase activity; serine-type endopeptidase activity
Biological Process: proteolysis
Research Articles on KLK11
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Product Notes
The KLK11 klk11 (Catalog #AAA175534) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-Kallikrein 11 antibody reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Kallikrein 11 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the KLK11 klk11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Kallikrein 11, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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