Rabbit Insulin Like Growth Factor Binding Protein 3 ELISA Kit | IGFBP3 elisa kit

Rabbit Insulin Like Growth Factor Binding Protein 3 ELISA Kit

Cat. Num. AAA729839

• Gene Names: Igfbp3; IGF-BP3
• Reactivity: Rabbit
• Synonyms: Insulin Like Growth Factor Binding Protein 3; Rabbit Insulin Like Growth Factor Binding Protein 3 ELISA Kit; IGFBP3 elisa kit

• Reactivity: Rabbit

• Samples: Serum, plasma, Cell Culture Supernatants, body fluid and tissue homogenate
• Assay Type: Competitive
• Detection Range: 0.5-10ng/mL
• Sensitivity: 0.1ng/mL
• Preparation and Storage: Store all reagents at 2-8 degree C.

Typical Testing Data/Standard Curve (for reference only)

Product Categories/Family for IGFBP3 elisa kit

Cell Biology

NCBI and Uniprot Product Information

• NCBI GI #: 298231182
• NCBI GeneID: 24484
• NCBI Accession #: NP_036720.2
• NCBI GenBank Nucleotide #: NM_012588.2
• Molecular Weight: 31,680 Da
• NCBI Official Full Name: insulin-like growth factor-binding protein 3
• NCBI Official Synonym Full Names: insulin-like growth factor binding protein 3
• NCBI Official Symbol: Igfbp3
• NCBI Official Synonym Symbols: IGF-BP3
• NCBI Protein Information: insulin-like growth factor-binding protein 3; IBP-3; IGFBP-3; IGF-binding protein 3; insulin-like growth factor-binding protein (IGF-BP3)
• UniProt Protein Name: Insulin-like growth factor-binding protein 3
• Protein Family: Insulin-like growth factor-binding protein
• UniProt Gene Name: Igfbp3
• UniProt Synonym Gene Names: Igfbp-3; IBP-3; IGF-binding protein 3; IGFBP-3
• UniProt Entry Name: IBP3_RAT

NCBI Description

an insulin growth factor (Igf) binding protein; involved in modulating IGF-I action [RGD, Feb 2006]

Uniprot Description

IGFBP3: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors. Also exhibits IGF-independent antiproliferative and apoptotic effects mediated by its receptor TMEM219/IGFBP-3R.

Protein type: Secreted, signal peptide; Secreted; Cell development/differentiation

Cellular Component: extracellular space; nucleus

Molecular Function: insulin-like growth factor binding; protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding; protein tyrosine phosphatase activator activity

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; positive regulation of catalytic activity; osteoblast differentiation; negative regulation of cell proliferation; regulation of insulin-like growth factor receptor signaling pathway; negative regulation of protein amino acid phosphorylation; positive regulation of MAPKKK cascade; positive regulation of apoptosis; negative regulation of smooth muscle cell proliferation; regulation of growth; negative regulation of smooth muscle cell migration; regulation of cell growth; protein amino acid phosphorylation; positive regulation of myoblast differentiation