SDS-PAGE
ICAM-2 / CD102 recombinant protein
Recombinant Mouse ICAM-2 / CD102 Protein
Gene Names
Icam2; CD102; Ly-60; Icam-2
Purity
> 85 % as determined by SDS-PAGE
Synonyms
ICAM-2 / CD102; Recombinant Mouse ICAM-2 / CD102 Protein; ICAM2; CD102; ICAM-2 / CD102 recombinant protein
Host
Human Cells
Purity/Purification
> 85 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
277
Application Notes
The recombinant mouse ICAM2 consists of 210 amino acids and has a calculated molecular mass of 23.6 kDa. The recombinant protein migrates as an approximately 38-42 kDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
Ser 20
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
SDS-PAGE
SDS-PAGE
Related Product Information for ICAM-2 / CD102 recombinant protein
Background: Intercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains, and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As a second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in identification of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Description: A DNA sequence encoding the mouse ICAM2 (NP_034624.1) (Met 1-Gln 222)was expressed with six amino acids (LEVLFQ) at the C-terminus.
Description: A DNA sequence encoding the mouse ICAM2 (NP_034624.1) (Met 1-Gln 222)was expressed with six amino acids (LEVLFQ) at the C-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,390 Da
NCBI Official Full Name
intercellular adhesion molecule 2
NCBI Official Synonym Full Names
intercellular adhesion molecule 2
NCBI Official Symbol
Icam2
NCBI Official Synonym Symbols
CD102; Ly-60; Icam-2
NCBI Protein Information
intercellular adhesion molecule 2
UniProt Protein Name
Intercellular adhesion molecule 2
UniProt Gene Name
Icam2
UniProt Synonym Gene Names
Icam-2; ICAM-2
Uniprot Description
ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.
Protein type: Cell adhesion; Membrane protein, integral
Chromosomal Location of Human Ortholog: 11 E1|11 69.09 cM
Cellular Component: integral to plasma membrane; membrane; plasma membrane; uropod
Molecular Function: integrin binding; protein binding
Biological Process: cell adhesion
Research Articles on ICAM-2 / CD102
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Product Notes
The ICAM-2 / CD102 icam2 (Catalog #AAA2546867) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse ICAM2 consists of 210 amino acids and has a calculated molecular mass of 23.6 kDa. The recombinant protein migrates as an approximately 38-42 kDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the ICAM-2 / CD102 icam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ICAM-2 / CD102, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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