Testing Data
Rabbit ICAM-2 Polyclonal Antibody | anti-ICAM-2 antibody
ICAM-2 Antibody
Gene Names
Icam2; CD102; Ly-60; Icam-2
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry
Purity
Affinity purified
Synonyms
ICAM-2; Polyclonal Antibody; ICAM-2 Antibody; ICAM1; P3.58; BB2; CD54; anti-ICAM-2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purified
Form/Format
100 ug (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Appearance: Colorless liquid
Appearance: Colorless liquid
Concentration
0.5 mg/ml (varies by lot)
Sequence Length
277
Applicable Applications for anti-ICAM-2 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
Western blotting (0.5-4 ug/ml) and Immunohistochemistry (5 ug/ml). It detects multiple isoforms of ICAM-2. However, the optimal concentrations should be determined individually.
Immunogen
Synthetic peptide surrounding amino acid 257 of mouse ICAM-2
Positive Control
Western Blot: Jurkat cell lysate and 3T3 cell lysate. IHC: spleen tissue
Handling
The antibody solution should be gently mixed before use.
Preparation and Storage
At -20 degree C
Shelf Life: 12 months
Shelf Life: 12 months
Testing Data
Testing Data
Related Product Information for anti-ICAM-2 antibody
Background: Cell adhesion molecules (CAMs) are a family of closely related cell surface glycoproteins involved in cell-cell interactions during growth and are thomught to play an important role in embryogenesis and development. The family contains NCAM (for neuronal cell adhesion molecule), ICAM (for intercellular adhesion molecule), VCAM (vascular cell adhesion molecule), PECAM-1 (platelet/endothelial cell adhesion molecule-1), etc. ICAM-2 is involved in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
31,390 Da
NCBI Official Full Name
intercellular adhesion molecule 2
NCBI Official Synonym Full Names
intercellular adhesion molecule 2
NCBI Official Symbol
Icam2
NCBI Official Synonym Symbols
CD102; Ly-60; Icam-2
NCBI Protein Information
intercellular adhesion molecule 2
UniProt Protein Name
Intercellular adhesion molecule 2
UniProt Gene Name
Icam2
UniProt Synonym Gene Names
Icam-2; ICAM-2
UniProt Entry Name
ICAM2_MOUSE
Uniprot Description
ICAM2: ICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). ICAM2 may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen- specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Belongs to the immunoglobulin superfamily. ICAM family.
Protein type: Membrane protein, integral; Cell adhesion
Cellular Component: membrane; integral to plasma membrane; integral to membrane; plasma membrane; uropod
Molecular Function: integrin binding; protein binding
Biological Process: cell-cell adhesion; cellular response to stimulus; cell adhesion
Research Articles on ICAM-2
Similar Products
Product Notes
The ICAM-2 icam2 (Catalog #AAA841258) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ICAM-2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ICAM-2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Western blotting (0.5-4 ug/ml) and Immunohistochemistry (5 ug/ml). It detects multiple isoforms of ICAM-2. However, the optimal concentrations should be determined individually. Researchers should empirically determine the suitability of the ICAM-2 icam2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ICAM-2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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