Human Neuropeptide Y Receptor Y1 (NPY1R) RTU ELISA Kit | NPY1R rtu elisa kit

Human Neuropeptide Y Receptor Y1 (NPY1R) ELISA Kit

Cat. Num. AAA4501450

• Gene Names: NPY1R; NPYR; NPY1-R
• Reactivity: Human
• Synonyms: Neuropeptide Y Receptor Y1 (NPY1R); Human Neuropeptide Y Receptor Y1 (NPY1R) ELISA Kit; NPYR; NPYY1; NPY1R rtu elisa kit

• Reactivity: Human
• Sequence Length: 384

• Assay Type: Sandwich
• Samples: Tissue Homogenates or Other Biological Fluids.
• Detection Range: 0.312-20ng/mL
• Sensitivity: 0.122ng/mL
• RTU ELISA Kit's Advantage: The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
• Preparation and Storage: For unopened kits: All the reagents should be kept at 4 degree C upon receipt.; For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for NPY1R rtu elisa kit

Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to NPY1R. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to NPY1R. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain NPY1R, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of NPY1R in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 4505445
• NCBI GeneID: 4886
• NCBI Accession #: NP_000900.1
• NCBI GenBank Nucleotide #: NM_000909.5
• UniProt Accession #: P25929; B2R6H5
• Molecular Weight: 44,392 Da
• NCBI Official Full Name: neuropeptide Y receptor type 1
• NCBI Official Synonym Full Names: neuropeptide Y receptor Y1
• NCBI Official Symbol: NPY1R
• NCBI Official Synonym Symbols: NPYR; NPY1-R
• NCBI Protein Information: neuropeptide Y receptor type 1
• UniProt Protein Name: Neuropeptide Y receptor type 1
• Protein Family: Neuropeptide Y receptor
• UniProt Gene Name: NPY1R
• UniProt Synonym Gene Names: NPYR; NPYY1; NPY1-R

NCBI Description

This gene belongs to the G-protein-coupled receptor superfamily. The encoded transmembrane protein mediates the function of neuropeptide Y (NPY), a neurotransmitter, and peptide YY (PYY), a gastrointestinal hormone. The encoded receptor undergoes fast agonist-induced internalization through clathrin-coated pits and is subsequently recycled back to the cell membrane. Activation of Y1 receptors may result in mobilization of intracellular calcium and inhibition of adenylate cyclase activity. [provided by RefSeq, Aug 2013]

Uniprot Description

Receptor for neuropeptide Y and peptide YY. The rank order of affinity of this receptor for pancreatic polypeptides is NPY > [Pro-34] PYY, PYY and [Leu-31, Pro-34] NPY > NPY (2-36) > [Ile-31, Gln-34] PP and PYY (3-36) > PP > NPY free acid.