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Typical Testing Data/Standard Curve (for reference only)

Human Desmocollin 2 (DSC2) RTU ELISA Kit | DSC2 rtu elisa kit

Human Desmocollin 2 (DSC2) ELISA Kit

Gene Names
DSC2; DG2; DSC3; CDHF2; ARVD11; DGII/III
Reactivity
Human
Synonyms
Desmocollin 2 (DSC2); Human Desmocollin 2 (DSC2) ELISA Kit; ARVD11; CDHF2; DG2; DGII/III; Cadherin family member 2; Desmosomal glycoprotein III; DSC2 rtu elisa kit
Ordering
For Research Use Only!
Reactivity
Human
Sequence Length
847
Assay Type
Sandwich
Samples
Tissue Homogenates or Other Biological Fluids.
Detection Range
0.312-20ng/mL
Sensitivity
0.107ng/mL
RTU ELISA Kit's Advantage
The Ready-To-Use (RTU) Kits require fewer steps in setup and take less time to run. Detection Solutions are pre-diluted and total incubation time is shorter than many other ELISA Kits.
Preparation and Storage
For unopened kits: All the reagents should be kept at 4 degree C upon receipt.
For opened kits: Once the kit is opened, the remaining reagents still need to be stored according to the above storage conditions. In addition, return the unused wells to the foil pouch containing the desiccant pack and reseal along entire edge of zip-seal.

Typical Testing Data/Standard Curve (for reference only)

Typical Testing Data/Standard Curve (for reference only)
Related Product Information for DSC2 rtu elisa kit
Test Principle: The microtiter plate provided in this kit has been pre-coated with an antibody specific to DSC2. Standards or samples are then added to the appropriate microtiter plate wells with a biotin-conjugated antibody preparation specific to DSC2. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain DSC2, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of DSC2 in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93,769 Da
NCBI Official Full Name
desmocollin-2 isoform Dsc2b preproprotein
NCBI Official Synonym Full Names
desmocollin 2
NCBI Official Symbol
DSC2
NCBI Official Synonym Symbols
DG2; DSC3; CDHF2; ARVD11; DGII/III
NCBI Protein Information
desmocollin-2
UniProt Protein Name
Desmocollin-2
Protein Family
UniProt Gene Name
DSC2

NCBI Description

This gene encodes a member of the desmocollin protein subfamily. Desmocollins, along with desmogleins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmocollin family members on chromosome 18. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia-11, and reduced protein expression has been described in several types of cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Uniprot Description

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

Research Articles on DSC2

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Product Notes

The Human DSC2 dsc2 (Catalog #AAA458931) is a RTU ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA458931 RTU ELISA Kit recognizes Human DSC2. It is sometimes possible for the material contained within the vial of "Desmocollin 2 (DSC2), RTU ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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