SDS-Page
Ferric uptake regulator (FuR) Recombinant Protein | FuR recombinant protein
Ferric uptake regulator (FuR), 1-148aa, E Coli, E Coli
Gene Names
fur; ECK0671; JW0669
Applications
SDS-Page
Purity
> 95% by SDS-PAGE
Synonyms
Ferric uptake regulator (FuR); 1-148aa; E Coli; DNA-binding transcriptional dual regulator of siderophore biosynthesis and transport; Ferric uptake regulator; FuR; ECK0671; Ferric uptake regulation protein; JW0669.; FuR recombinant protein
Host
E Coli
Purity/Purification
> 95% by SDS-PAGE
Form/Format
Liquid in 20mM Tris pH 8.0, 2mM CaCl2, 100mM NaCl
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI RLTNHSLYLY GHCAEGDCRE DEHAHEGK
Sequence Length
148
Applicable Applications for FuR recombinant protein
SDS-PAGE
Antigen Species
Human
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for FuR recombinant protein
Fur (ferric uptake regulator) protein is a DNA-binding protein which regulates iron-responsive genes. Fur is a small, 17-kDa, global transcriptional repressor that in the presence of iron regulates functions as diverse as iron acquisition, oxidative stress, and virulence. In Escherichia coli, members of the Fur family regulate the expression of more than 100 genes that function in processes as varied as the biosynthesis and transport of siderophores, the expression of virulence factors, the alleviation of oxidative and NO-induced stress, and the inhibition of ferritin production through the expression of RyhB. Recombinant FuR was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for FuR recombinant protein
References
O'Sullivan DJ., et al. (1994). FEMS Microbiol Lett. Apr 15; 117 (3):327-32; Mills SA., et al. (2005) Biochemistry. Oct 18; 44 (41):13553-9;
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
16.7kDa (148aa), confirmed by MALDI-TOF.
NCBI Official Full Name
ferric iron uptake regulon transcriptional repressor; autorepressor
NCBI Official Symbol
fur
NCBI Official Synonym Symbols
ECK0671; JW0669
NCBI Protein Information
ferric iron uptake regulon transcriptional repressor; autorepressor
UniProt Protein Name
Ferric uptake regulation protein
Protein Family
UniProt Gene Name
fur
UniProt Synonym Gene Names
Ferric uptake regulator
NCBI Description
Fur translation in coupled to the translation of the upstream leader pepidie Uof; Uof translation is inhibited by the antisense sRNA ryhB; Uof translation opens up a hairpin that blocks Fur translation (Vecerek, 2007). [More information is available at EcoGene: EG10359].
Uniprot Description
Acts as a global negative controlling element, employing Fe2+ as a cofactor to bind the operator of the repressed genes. Regulates the expression of several outer-membrane proteins including the iron transport operon.
Research Articles on FuR
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Product Notes
The FuR fur (Catalog #AAA203197) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Ferric uptake regulator (FuR) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the FuR fur for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MTDNNTALKK AGLKVTLPRL KILEVLQEPD NHHVSAEDLY KRLIDMGEEI GLATVYRVLN QFDDAGIVTR HNFEGGKSVF ELTQQHHHDH LICLDCGKVI EFSDDSIEAR QREIAAKHGI RLTNHSLYLY GHCAEGDCRE DEHAHEGK. It is sometimes possible for the material contained within the vial of "Ferric uptake regulator (FuR), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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