Testing Data
TAU Antibody | anti-Tau antibody
TAU, Affinity Purified Antibody, Chicken
Reactivity
Human, Mouse, Rat
Applications
Immunocytochemistry, Immunohistochemistry
Synonyms
TAU; Affinity Purified Antibody; Chicken; anti-Tau antibody
Reactivity
Human, Mouse, Rat
Form/Format
Affinity Purified - Liquid
Sequence Length
192
Applicable Applications for anti-Tau antibody
Immunocytochemistry (ICC), Immunohistochemistry (IHC)
Type Info
Chicken IgY
Immunogen
Chicken synthetic peptide/keyhole limpet hemocyanin (KLH) conjugates corresponding to two regions of the Tau gene product. These peptides corresponded to sequences shared between the mouse (P01637) and human (NP_05819) proteins, and did not contain any of the serine and threonine residues known to undergo phosphorylation.
Preparation and Storage
Store at 4-8 degrees
Testing Data
Testing Data
Related Product Information for anti-Tau antibody
Tau is a heterogeneous microtubule-associated protein that promotes and stabilizes microtubule assembly, especially in axons. Six isoforms with different amino-terminal inserts and different numbers of tandem repeats near the carboxy-terminus have been identified, and tau is hyperphosphorylated at approximately 25 sites by ERK, GSK-3 and CDK5. Phosphorylation decreases the ability of tau to bind to microtubules. Neurofibrillary tangles are a major hallmark of Alzheimer's disease and these tangles are bundles of paired helical filaments composed of hyperphosphorylated tau. In particular, phosphorylation of Ser396 by GSK-3 or CDK5 destabilizes microtubules in Alzheimer's disease. Furthermore, inclusions of tau are found in a number of other neurodegenerative diseases, collectively known as tauopathies.
Product Categories/Family for anti-Tau antibody
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
19,593 Da
NCBI Official Full Name
TAU, partial
UniProt Protein Name
Microtubule-associated protein
Protein Family
UniProt Gene Name
TAU
UniProt Entry Name
A0A0S7LKS6_9TELE
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Product Notes
The Tau tau (Catalog #AAA555375) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The TAU, Affinity Purified Antibody, Chicken reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's TAU can be used in a range of immunoassay formats including, but not limited to, Immunocytochemistry (ICC), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the Tau tau for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TAU, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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