Testing Data
(Peptide-+)
PMP22 Antibody | anti-PMP22 antibody
PMP22 Antibody
Gene Names
PMP22; DSS; CIDP; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA
Reactivity
Human, Mouse, Rat
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
PMP22; PMP22 Antibody; GAS3; GROWTH ARREST-SPECIFIC 3; anti-PMP22 antibody
Reactivity
Human, Mouse, Rat
Specificity
PMP22 antibody detects endogenous levels of total PMP22 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
160
Applicable Applications for anti-PMP22 antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:40000
IHC: 1:50~1:100
ELISA: 1:40000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human PMP22.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using PMP22 antibody. Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 antibody.)
Immunohistochemistry (IHC)
(Immunohistochemical analysis of paraffin-embedded human brain tissue using PMP22 antibody. Western blot analysis of extracts from MDA-MB-435 cells, using PMP22 antibody.)
References
GJ Snipes, J. Cell Biol., Apr 1992; 117: 225. P A Csurhes, J. Neurol. Neurosurg. Psychiatry, Oct 2005; 76: 1431-1439. Laura D. Attardi, Genes & Dev., Mar 2000; 14: 704. Julie A. Hodapp, Arch Neurol, Jan 2006; 63: 112-117.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
17,891 Da
NCBI Official Full Name
peripheral myelin protein 22 isoform 1
NCBI Official Synonym Full Names
peripheral myelin protein 22
NCBI Official Symbol
PMP22
NCBI Official Synonym Symbols
DSS; CIDP; GAS3; HNPP; CMT1A; CMT1E; GAS-3; Sp110; HMSNIA
NCBI Protein Information
peripheral myelin protein 22
UniProt Protein Name
Peripheral myelin protein 22
Protein Family
UniProt Gene Name
PMP22
UniProt Synonym Gene Names
GAS3; PMP-22; GAS-3
NCBI Description
This gene encodes an integral membrane protein that is a major component of myelin in the peripheral nervous system. Studies suggest two alternately used promoters drive tissue-specific expression. Various mutations of this gene are causes of Charcot-Marie-Tooth disease Type IA, Dejerine-Sottas syndrome, and hereditary neuropathy with liability to pressure palsies. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Uniprot Description
Might be involved in growth regulation, and in myelinization in the peripheral nervous system.
Research Articles on PMP22
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Product Notes
The PMP22 pmp22 (Catalog #AAA8509385) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The PMP22 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's PMP22 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:40000. Researchers should empirically determine the suitability of the PMP22 pmp22 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PMP22, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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