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Western Blot (WB) (Western blot analysis of extracts from K562 cells, using MCPH1 antibody.)

anti-Human, Mouse MCPH1 Antibody | anti-MCPH1 antibody

MCPH1 Antibody

Gene Names
MCPH1; MCT; BRIT1
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry
Purity
Immunogen affinity purified
Synonyms
MCPH1; MCPH1 Antibody; Microcephalin; anti-MCPH1 antibody
Ordering
For Research Use Only!
Reactivity
Human, Mouse
Specificity
MCPH1 Antibody detects endogenous levels of total MCPH1
Purity/Purification
Immunogen affinity purified
Form/Format
In phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
610
Applicable Applications for anti-MCPH1 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:200
Immunogen
A synthesized peptide
Preparation and Storage
Store at-20 degree C for 1 year

Western Blot (WB)

(Western blot analysis of extracts from K562 cells, using MCPH1 antibody.)

Western Blot (WB) (Western blot analysis of extracts from K562 cells, using MCPH1 antibody.)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
93 KD
NCBI Official Full Name
microcephalin isoform 2
NCBI Official Synonym Full Names
microcephalin 1
NCBI Official Symbol
MCPH1
NCBI Official Synonym Symbols
MCT; BRIT1
NCBI Protein Information
microcephalin
UniProt Protein Name
Microcephalin
Protein Family
UniProt Gene Name
MCPH1

NCBI Description

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2010]

Uniprot Description

Implicated in chromosome condensation and DNA damage induced cellular responses. May play a role in neurogenesis and regulation of the size of the cerebral cortex.

Research Articles on MCPH1

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Product Notes

The MCPH1 mcph1 (Catalog #AAA8515534) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The MCPH1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's MCPH1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). WB: 1:500~1:1000 IHC: 1:50~1:200. Researchers should empirically determine the suitability of the MCPH1 mcph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "MCPH1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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