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Immunohistochemistry (IHC) (Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))

Rabbit anti-Human PPFIBP1 Polyclonal Antibody | anti-PPFIBP1 antibody

Anti-PPFIBP1 Antibody (aa588-617)

Gene Names
PPFIBP1; L2; SGT2; hSGT2; hSgt2p
Reactivity
Human
Applications
Immunohistochemistry, Western Blot
Purity
Protein A purified
Synonyms
PPFIBP1; Polyclonal Antibody; Anti-PPFIBP1 Antibody (aa588-617); Rabbit Polyclonal (IgG) to Human PPFIBP1; HSGT2; Liprin-beta-1; L2; Liprin related protein; Liprin-beta 1; HSgt2p; KIAA1230; SGT2; anti-PPFIBP1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human
Clonality
Polyclonal
Specificity
This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.
Purity/Purification
Protein A purified
Form/Format
PBS, 0.09% sodium azide
Sequence Length
1005
Applicable Applications for anti-PPFIBP1 antibody
Immunohistochemistry (IHC) Paraffin, Western Blot (WB)
Application Notes
IHC-P: 1:100
WB: 1:2000
Conjugation
Unconjugated
Epitope
aa588-617
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months.
For long term storage store at -20 degree C.

Immunohistochemistry (IHC)

(Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))

Immunohistochemistry (IHC) (Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE))

Western Blot (WB)

(Anti-PPFIBP1 Antibody at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.)

Western Blot (WB) (Anti-PPFIBP1 Antibody at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 ug per lane.)
Related Product Information for anti-PPFIBP1 antibody
member of the LAR protein -tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family oftransmembrane protein tyrosine phosphatases, which are known to beimportant for axon guidance and mammary gl and development. It has beenproposed that liprins are multivalent proteins that form complexstructures and act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
18,972 Da
NCBI Official Full Name
liprin-beta-1 isoform 1
NCBI Official Synonym Full Names
PPFIA binding protein 1
NCBI Official Symbol
PPFIBP1
NCBI Official Synonym Symbols
L2; SGT2; hSGT2; hSgt2p
NCBI Protein Information
liprin-beta-1
UniProt Protein Name
Liprin-beta-1
Protein Family
UniProt Gene Name
PPFIBP1
UniProt Synonym Gene Names
KIAA1230; PTPRF-interacting protein-binding protein 1

NCBI Description

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Uniprot Description

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.

Research Articles on PPFIBP1

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Product Notes

The PPFIBP1 ppfibp1 (Catalog #AAA2401830) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-PPFIBP1 Antibody (aa588-617) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's PPFIBP1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Paraffin, Western Blot (WB). IHC-P: 1:100 WB: 1:2000. Researchers should empirically determine the suitability of the PPFIBP1 ppfibp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PPFIBP1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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