Testing Data
(Peptide-+)
anti-Human, Mouse DUS2L Antibody | anti-DUS2L antibody
DUS2L Antibody
Gene Names
DUS2; SMM1; DUS2L; URLC8
Reactivity
Human, Mouse
Applications
Western Blot, Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
DUS2L; DUS2L Antibody; tRNA-dihydrouridine synthase 2-like; EC 1.-.-.-; hDUS2; Up-regulated in lung cancer; URLC8; DUS2; anti-DUS2L antibody
Reactivity
Human, Mouse
Specificity
DUS2L antibody detects endogenous levels of total DUS2L protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
493
Applicable Applications for anti-DUS2L antibody
Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
WB: 1:500~1:1000
IHC: 1:50~1:100
ELISA: 1:20000
IHC: 1:50~1:100
ELISA: 1:20000
Immunogen
The antiserum was produced against synthesized peptide derived from C-terminal of human DUS2L.
Preparation and Storage
Store at-20 degree C for 1 year.
Testing Data
(Peptide-+)
Testing Data
(Peptide-+)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L antibody. Western blot analysis of extracts from RAW264.7 cells, using DUS2L antibody.)
Immunohistochemistry (IHC)
(Immunohistochemistry analysis of paraffin-embedded human skeletal muscle using DUS2L antibody. Western blot analysis of extracts from RAW264.7 cells, using DUS2L antibody.)
Product Categories/Family for anti-DUS2L antibody
References
Ota T., Nat. Genet. 36:40-45(2004). The MGC Project Team; Genome Res. 14:2121-2127(2004). Kato T., Cancer Res. 65:5638-5646(2005).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
55,050 Da
NCBI Official Full Name
tRNA-dihydrouridine(20) synthase
NCBI Official Synonym Full Names
dihydrouridine synthase 2
NCBI Official Symbol
DUS2
NCBI Official Synonym Symbols
SMM1; DUS2L; URLC8
NCBI Protein Information
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
UniProt Protein Name
tRNA-dihydrouridine(20) synthase [NAD(P)+]-like
UniProt Gene Name
DUS2
UniProt Synonym Gene Names
DUS2L; URLC8; hDUS2
NCBI Description
This gene encodes a cytoplasmic protein that catalyzes the conversion of uridine residues to dihydrouridine in the D-loop of tRNA. The resulting modified bases confer enhanced regional flexibility to tRNA. The encoded protein may increase the rate of translation by inhibiting an interferon-induced protein kinase. This gene has been implicated in pulmonary carcinogenesis. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Nov 2012]
Uniprot Description
Dihydrouridine synthase. Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. Negatively regulates the activation of EIF2AK2/PKR.
Research Articles on DUS2L
Similar Products
Product Notes
The DUS2L dus2 (Catalog #AAA853294) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The DUS2L Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's DUS2L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), ELISA (EIA). WB: 1:500~1:1000 IHC: 1:50~1:100 ELISA: 1:20000. Researchers should empirically determine the suitability of the DUS2L dus2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "DUS2L, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
