Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using AMOTL1 antibody.)
anti-Human, Mouse AMOTL1 Antibody | anti-AMOTL1 antibody
AMOTL1 Antibody
Gene Names
AMOTL1; JEAP
Reactivity
Human, Mouse
Applications
Immunohistochemistry, ELISA
Purity
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Synonyms
AMOTL1; AMOTL1 Antibody; Angiomotin-like protein 1; anti-AMOTL1 antibody
Reactivity
Human, Mouse
Specificity
AMOTL1 antibody detects endogenous levels of total AMOTL1 protein.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Sequence Length
906
Applicable Applications for anti-AMOTL1 antibody
Immunohistochemistry (IHC), ELISA (EIA)
Application Notes
IHC: 1:50-1:100
ELISA: 1:10000
ELISA: 1:10000
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human AMOTL1.
Preparation and Storage
Store at-20 degree C for 1 year.
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using AMOTL1 antibody.)
Immunohistochemistry (IHC)
(Peptide-+ Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue using AMOTL1 antibody.)
Product Categories/Family for anti-AMOTL1 antibody
References
Bratt A., Gene 298:69-77(2002). Bratt A., Gene 310:231-231(2003). Yu L.-R., J. Proteome Res. 6:4150-4162(2007).
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
101,179 Da
NCBI Official Full Name
angiomotin-like protein 1 isoform 2
NCBI Official Synonym Full Names
angiomotin like 1
NCBI Official Symbol
AMOTL1
NCBI Official Synonym Symbols
JEAP
NCBI Protein Information
angiomotin-like protein 1
UniProt Protein Name
Angiomotin-like protein 1
Protein Family
UniProt Gene Name
AMOTL1
NCBI Description
The protein encoded by this gene is a peripheral membrane protein that is a component of tight junctions or TJs. TJs form an apical junctional structure and act to control paracellular permeability and maintain cell polarity. This protein is related to angiomotin, an angiostatin binding protein that regulates endothelial cell migration and capillary formation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Uniprot Description
Inhibits the Wnt/beta-catenin signaling pathway, probably by recruiting CTNNB1 to recycling endosomes and hence preventing its translocation to the nucleus.
Research Articles on AMOTL1
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Product Notes
The AMOTL1 amotl1 (Catalog #AAA856491) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. The AMOTL1 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's AMOTL1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC), ELISA (EIA). IHC: 1:50-1:100 ELISA: 1:10000. Researchers should empirically determine the suitability of the AMOTL1 amotl1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "AMOTL1, Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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