Human Vascular Endothelial Cell Growth Factor Receptor 2 ELISA Kit | Kdr elisa kit

Human Vascular Endothelial Cell Growth Factor Receptor 2 ELISA Kit

Cat. Num. AAA3804426

• Gene Names: Kdr; Vegfr-2
• Reactivity: Human
• Synonyms: Vascular Endothelial Cell Growth Factor Receptor 2; Human Vascular Endothelial Cell Growth Factor Receptor 2 ELISA Kit; Kdr elisa kit

• Reactivity: Human
• Sequence Length: 1343

• Samples: Serum, plasma, cell culture supernate and other biological fluids
• Assay Type: Sandwich
• Detection Range: 1.25ng/ml-20ng/ml
• Sensitivity: 0.1 ng/ml

Typical Testing Data/Standard Curve (for reference only)

Related Product Information for Kdr elisa kit

Intended Use: The Stop Solution changes the color from blue to yellow and the intensity of the color is measured at 450 nm using a spectrophotometer. In order to measure the concentration ofVASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR 2in the sample, This VASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR 2ELISA Kit includes a set of calibration standards. The calibration standards are assayed at the same time as the samples and allow the operator to produce a standard curve of Optical Density versusVASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR 2concentration. The concentration ofVASCULAR ENDOTHELIAL CELL GROWTH FACTOR RECEPTOR 2in the samples is then determined by comparing the O.D. of the samples to the standard curve.

NCBI and Uniprot Product Information

• NCBI GI #: 6981128
• NCBI GeneID: 25589
• NCBI Accession #: NP_037194.1
• NCBI GenBank Nucleotide #: NP_037194.1
• UniProt Accession #: O08775
• NCBI Official Full Name: vascular endothelial growth factor receptor 2
• NCBI Official Synonym Full Names: kinase insert domain receptor
• NCBI Official Symbol: Kdr
• NCBI Official Synonym Symbols: Vegfr-2
• NCBI Protein Information: vascular endothelial growth factor receptor 2
• UniProt Protein Name: Vascular endothelial growth factor receptor 2
• Protein Family: Vascular endothelial growth factor receptor
• UniProt Gene Name: Kdr
• UniProt Synonym Gene Names: Flk1; VEGFR-2; FLK-1

NCBI Description

receptor for vascular endothelial growth factor (VEGF) [RGD, Feb 2006]

Uniprot Description

VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability.

Protein type: EC 2.7.10.1; Kinase, protein; Membrane protein, integral; Protein kinase, TK; Protein kinase, tyrosine (receptor); TK group; VEGFR family

Chromosomal Location of Human Ortholog: 14p11

Cellular Component: cell junction; cell periphery; cell soma; cell surface; cytoplasm; early endosome; endoplasmic reticulum; endosome; external side of plasma membrane; Golgi apparatus; integral component of membrane; integral component of plasma membrane; membrane raft; neuron projection; nucleus; plasma membrane

Molecular Function: ATP binding; growth factor binding; identical protein binding; integrin binding; protein binding; protein tyrosine kinase activity; vascular endothelial growth factor binding; vascular endothelial growth factor-activated receptor activity

Biological Process: aging; alveolus development; angiogenesis; branching morphogenesis of a tube; calcium ion homeostasis; cell fate commitment; cell maturation; cell migration; cell migration during sprouting angiogenesis; elevation of cytosolic calcium ion concentration; embryonic hemopoiesis; endocardium development; endochondral bone growth; endothelial cell differentiation; endothelium development; ERK1 and ERK2 cascade; hemopoiesis; hyaluronan metabolic process; lung development; lymph vessel development; male gonad development; negative regulation of apoptosis; negative regulation of endothelial cell apoptotic process; negative regulation of neuron apoptosis; neuron projection morphogenesis; ovarian follicle development; peptidyl-tyrosine autophosphorylation; peptidyl-tyrosine phosphorylation; positive regulation of angiogenesis; positive regulation of blood vessel diameter; positive regulation of BMP signaling pathway; positive regulation of calcium-mediated signaling; positive regulation of cell migration; positive regulation of cell proliferation; positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway; positive regulation of endothelial cell migration; positive regulation of endothelial cell proliferation; positive regulation of epithelial cell proliferation; positive regulation of ERK1 and ERK2 cascade; positive regulation of focal adhesion assembly; positive regulation of long-term neuronal synaptic plasticity; positive regulation of macroautophagy; positive regulation of MAPK cascade; positive regulation of mesenchymal cell proliferation; positive regulation of mitochondrial depolarization; positive regulation of mitochondrial fission; positive regulation of neurogenesis; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of positive chemotaxis; positive regulation of protein phosphorylation; positive regulation of TOR signaling pathway; positive regulation of vasculogenesis; post-embryonic camera-type eye morphogenesis; protein autophosphorylation; protein kinase B signaling; regulation of cell shape; regulation of endothelial cell differentiation; regulation of hematopoietic progenitor cell differentiation; response to drug; response to hypoxia; surfactant homeostasis; vascular endothelial growth factor receptor signaling pathway; vascular endothelial growth factor signaling pathway; vasculogenesis